Cremastranone

Details

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Internal ID 157fb133-b449-4aef-a99b-e0281748bd66
Taxonomy Phenylpropanoids and polyketides > Homoisoflavonoids > Homoisoflavans > Homoisoflavanones
IUPAC Name 5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2,3-dihydrochromen-4-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H18O7/c1-23-13-4-3-9(6-11(13)19)5-10-8-25-14-7-12(20)18(24-2)17(22)15(14)16(10)21/h3-4,6-7,10,19-20,22H,5,8H2,1-2H3
InChI Key DSTDMPAJBBOFCE-UHFFFAOYSA-N
Popularity 11 references in papers

Physical and Chemical Properties

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Molecular Formula C18H18O7
Molecular Weight 346.30 g/mol
Exact Mass 346.10525291 g/mol
Topological Polar Surface Area (TPSA) 105.00 Ų
XlogP 2.80

Synonyms

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CHEBI:132956
5,7-dihydroxy-3-(3-hydroxy-4-methoxybenzyl)-6-methoxychroman-4-one
5,7-dihydroxy-3-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2,3-dihydrochromen-4-one
5,7-dihydroxy-HMBMC
5,7-dihydroxy-3-((3-hydroxy-4-methoxyphenyl)methyl)-6-methoxy-2,3-dihydrochromen-4-one
RefChem:128435
GlyTouCan:G89309PH
G89309PH
107585-69-3 (racemic)
107585-69-3
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Cremastranone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.45% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.51% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.89% 96.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 94.59% 94.00%
CHEMBL2581 P07339 Cathepsin D 93.62% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.60% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.53% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.46% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.17% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.62% 89.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.56% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.31% 97.09%
CHEMBL2535 P11166 Glucose transporter 82.88% 98.75%
CHEMBL3192 Q9BY41 Histone deacetylase 8 82.34% 93.99%
CHEMBL4208 P20618 Proteasome component C5 82.28% 90.00%
CHEMBL5555 O00767 Acyl-CoA desaturase 80.08% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Cremastra appendiculata
Merwilla plumbea
Muscari armeniacum
Scilla luciliae

Cross-Links

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PubChem 21676260
NPASS NPC222814
ChEMBL CHEMBL3581076
LOTUS LTS0013307
wikiData Q104988018