3-(1H-Indol-3-ylmethyl)-6-methyl-2,5-piperazinedione

Details

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Internal ID d773548c-9964-46d7-add5-dbe37ea04974
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name 3-(1H-indol-3-ylmethyl)-6-methylpiperazine-2,5-dione
SMILES (Canonical) CC1C(=O)NC(C(=O)N1)CC2=CNC3=CC=CC=C32
SMILES (Isomeric) CC1C(=O)NC(C(=O)N1)CC2=CNC3=CC=CC=C32
InChI InChI=1S/C14H15N3O2/c1-8-13(18)17-12(14(19)16-8)6-9-7-15-11-5-3-2-4-10(9)11/h2-5,7-8,12,15H,6H2,1H3,(H,16,19)(H,17,18)
InChI Key VDMMFAOUINDEGC-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C14H15N3O2
Molecular Weight 257.29 g/mol
Exact Mass 257.116426730 g/mol
Topological Polar Surface Area (TPSA) 74.00 Ų
XlogP 1.20

Synonyms

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26384-48-5
SCHEMBL3121649
3-(1H-Indol-3-ylmethyl)-6-methyl-2,5-piperazinedione
3-((1H-indol-3-yl)methyl)-6-methylpiperazine-2,5-dione
CHEBI:182109
NCGC00380229-01
3-(1H-indol-3-ylmethyl)-6-methylpiperazine-2,5-dione

2D Structure

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2D Structure of 3-(1H-Indol-3-ylmethyl)-6-methyl-2,5-piperazinedione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.29% 91.11%
CHEMBL2581 P07339 Cathepsin D 95.18% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.69% 95.56%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 92.43% 90.71%
CHEMBL1937 Q92769 Histone deacetylase 2 91.44% 94.75%
CHEMBL1951 P21397 Monoamine oxidase A 90.87% 91.49%
CHEMBL3310 Q96DB2 Histone deacetylase 11 89.61% 88.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 87.62% 97.64%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.79% 90.08%
CHEMBL255 P29275 Adenosine A2b receptor 86.26% 98.59%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 85.87% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 84.30% 83.82%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.53% 93.99%
CHEMBL1949 P62937 Cyclophilin A 82.36% 98.57%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.53% 99.23%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 80.40% 83.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 15563753
LOTUS LTS0169020
wikiData Q105284251