3-(1H-indol-3-ylmethyl)-3,6-bis(methylsulfanyl)-6-propan-2-ylpiperazine-2,5-dione

Details

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Internal ID c53fa489-ddb9-4769-a5a8-95e84f451c17
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name 3-(1H-indol-3-ylmethyl)-3,6-bis(methylsulfanyl)-6-propan-2-ylpiperazine-2,5-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H23N3O2S2/c1-11(2)18(25-4)16(23)20-17(24-3,15(22)21-18)9-12-10-19-14-8-6-5-7-13(12)14/h5-8,10-11,19H,9H2,1-4H3,(H,20,23)(H,21,22)
InChI Key JXDWMFMAEDSXNI-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C18H23N3O2S2
Molecular Weight 377.50 g/mol
Exact Mass 377.12316933 g/mol
Topological Polar Surface Area (TPSA) 125.00 Ų
XlogP 3.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 3-(1H-indol-3-ylmethyl)-3,6-bis(methylsulfanyl)-6-propan-2-ylpiperazine-2,5-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.16% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.20% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.72% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 94.48% 94.75%
CHEMBL3310 Q96DB2 Histone deacetylase 11 94.34% 88.56%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 93.45% 83.10%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 92.77% 94.62%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.80% 90.08%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.49% 94.00%
CHEMBL2535 P11166 Glucose transporter 89.43% 98.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.38% 96.09%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 88.05% 90.71%
CHEMBL255 P29275 Adenosine A2b receptor 87.91% 98.59%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.42% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.45% 94.45%
CHEMBL1829 O15379 Histone deacetylase 3 83.08% 95.00%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 82.15% 94.08%
CHEMBL3192 Q9BY41 Histone deacetylase 8 82.01% 93.99%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 22297272
LOTUS LTS0084496
wikiData Q104169961