3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione

Details

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Internal ID c739e0e3-d624-47bd-8aa7-a32c3de90584
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives
IUPAC Name 3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H17N3O2/c20-15-14-6-3-7-19(14)16(21)13(18-15)8-10-9-17-12-5-2-1-4-11(10)12/h1-2,4-5,9,13-14,17H,3,6-8H2,(H,18,20)
InChI Key RYFZBPVMVYTEKZ-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C16H17N3O2
Molecular Weight 283.32 g/mol
Exact Mass 283.132076794 g/mol
Topological Polar Surface Area (TPSA) 65.20 Ų
XlogP 1.50

Synonyms

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MEGxm0_000121
SCHEMBL2039877
ACon0_001418
ACon1_002338
CHEBI:182578
BCP24252
AKOS032947322
FS-6947
NSC-351976
3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 3-(1H-indol-3-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.21% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.90% 98.95%
CHEMBL333 P08253 Matrix metalloproteinase-2 96.97% 96.31%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 95.31% 90.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.27% 95.56%
CHEMBL3310 Q96DB2 Histone deacetylase 11 95.12% 88.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.76% 97.64%
CHEMBL3524 P56524 Histone deacetylase 4 94.46% 92.97%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.31% 90.08%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.35% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.95% 96.09%
CHEMBL1978 P11511 Cytochrome P450 19A1 91.27% 91.76%
CHEMBL1902 P62942 FK506-binding protein 1A 91.14% 97.05%
CHEMBL321 P14780 Matrix metalloproteinase 9 89.66% 92.12%
CHEMBL217 P14416 Dopamine D2 receptor 89.48% 95.62%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 88.17% 96.39%
CHEMBL228 P31645 Serotonin transporter 87.89% 95.51%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.86% 95.89%
CHEMBL213 P08588 Beta-1 adrenergic receptor 87.48% 95.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 87.13% 93.99%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.52% 93.03%
CHEMBL1951 P21397 Monoamine oxidase A 86.34% 91.49%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 85.20% 89.62%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 85.07% 91.43%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.66% 89.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.36% 92.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.90% 99.23%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 83.70% 85.14%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 82.92% 92.67%
CHEMBL1937 Q92769 Histone deacetylase 2 82.86% 94.75%
CHEMBL5805 Q9NR97 Toll-like receptor 8 82.75% 96.25%
CHEMBL255 P29275 Adenosine A2b receptor 82.30% 98.59%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 82.10% 83.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 434562
LOTUS LTS0224225
wikiData Q105247550