(2S,2'R,3R,4E,8E)-N-2'-hydroxytetradecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol

Details

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Internal ID 7b80074a-885e-4548-8f0f-768ba65b34e5
Taxonomy Lipids and lipid-like molecules > Sphingolipids > Ceramides > Long-chain ceramides
IUPAC Name (2R)-N-[(2S,3R,4E,8E)-1,3-dihydroxy-9-methyloctadeca-4,8-dien-2-yl]-2-hydroxytetradecanamide
SMILES (Canonical) CCCCCCCCCCCCC(C(=O)NC(CO)C(C=CCCC=C(C)CCCCCCCCC)O)O
SMILES (Isomeric) CCCCCCCCCCCC[C@H](C(=O)N[C@@H](CO)[C@@H](/C=C/CC/C=C(\C)/CCCCCCCCC)O)O
InChI InChI=1S/C33H63NO4/c1-4-6-8-10-12-13-14-16-18-22-27-32(37)33(38)34-30(28-35)31(36)26-23-19-21-25-29(3)24-20-17-15-11-9-7-5-2/h23,25-26,30-32,35-37H,4-22,24,27-28H2,1-3H3,(H,34,38)/b26-23+,29-25+/t30-,31+,32+/m0/s1
InChI Key DEKGAKCJRCZBDX-VTPWMCFTSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C33H63NO4
Molecular Weight 537.90 g/mol
Exact Mass 537.47570949 g/mol
Topological Polar Surface Area (TPSA) 89.80 Ų
XlogP 10.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (2S,2'R,3R,4E,8E)-N-2'-hydroxytetradecanoyl-2-amino-9-methyl-4,8-octadecadiene-1,3-diol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 98.82% 92.08%
CHEMBL2581 P07339 Cathepsin D 98.58% 98.95%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.01% 99.17%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 97.19% 92.86%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 96.90% 97.29%
CHEMBL3359 P21462 Formyl peptide receptor 1 96.66% 93.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.41% 96.09%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 91.96% 91.24%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.59% 100.00%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 89.37% 91.81%
CHEMBL340 P08684 Cytochrome P450 3A4 89.10% 91.19%
CHEMBL4040 P28482 MAP kinase ERK2 88.04% 83.82%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 87.99% 94.33%
CHEMBL3401 O75469 Pregnane X receptor 86.69% 94.73%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 86.55% 100.00%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 86.46% 100.00%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 86.36% 85.94%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 85.93% 91.11%
CHEMBL230 P35354 Cyclooxygenase-2 85.61% 89.63%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 85.54% 92.29%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 85.11% 92.88%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.73% 90.71%
CHEMBL299 P17252 Protein kinase C alpha 83.90% 98.03%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 83.52% 97.21%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 83.36% 89.34%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 83.07% 96.90%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.17% 96.95%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 81.94% 98.75%
CHEMBL4015 P41597 C-C chemokine receptor type 2 81.20% 98.57%
CHEMBL3238 P23786 Carnitine palmitoyltransferase 2 80.81% 94.05%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 80.67% 96.67%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 80.58% 96.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.51% 96.47%
CHEMBL2514 O95665 Neurotensin receptor 2 80.35% 100.00%
CHEMBL2413 P32246 C-C chemokine receptor type 1 80.29% 89.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11060562
LOTUS LTS0207939
wikiData Q104977295