(2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-2,3-dimethyl-2,3-dihydronaphthalen-1-one

Details

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Internal ID d226b049-4f6f-43b3-ae90-a78d3874020c
Taxonomy Lignans, neolignans and related compounds > Aryltetralin lignans
IUPAC Name (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-2,3-dimethyl-2,3-dihydronaphthalen-1-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H22O6/c1-11-12(2)21(23,13-5-6-16-19(7-13)27-10-26-16)15-9-18(25-4)17(24-3)8-14(15)20(11)22/h5-9,11-12,23H,10H2,1-4H3/t11-,12-,21+/m1/s1
InChI Key NDCKQHZMIZHJRH-ZSMADZGOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H22O6
Molecular Weight 370.40 g/mol
Exact Mass 370.14163842 g/mol
Topological Polar Surface Area (TPSA) 74.20 Ų
XlogP 3.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-2,3-dimethyl-2,3-dihydronaphthalen-1-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 98.09% 96.77%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.54% 91.11%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 93.27% 94.80%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.70% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.89% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.96% 95.56%
CHEMBL2581 P07339 Cathepsin D 90.22% 98.95%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.21% 92.62%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.47% 85.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.17% 89.00%
CHEMBL4208 P20618 Proteasome component C5 86.81% 90.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.50% 97.14%
CHEMBL2535 P11166 Glucose transporter 86.16% 98.75%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 85.25% 82.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.23% 94.45%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.98% 92.94%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.76% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.14% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.53% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.93% 100.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.45% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Virola elongata
Virola sebifera

Cross-Links

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PubChem 14655053
LOTUS LTS0073536
wikiData Q105177488