(2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-2,4-dihydroxy-6,7-dimethoxy-2,3-dimethyl-3H-naphthalen-1-one

Details

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Internal ID ba3588c6-e9d4-46c2-9d3a-131b04ab3068
Taxonomy Lignans, neolignans and related compounds > Aryltetralin lignans
IUPAC Name (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-2,4-dihydroxy-6,7-dimethoxy-2,3-dimethyl-3H-naphthalen-1-one
SMILES (Canonical) CC1C(C(=O)C2=CC(=C(C=C2C1(C3=CC4=C(C=C3)OCO4)O)OC)OC)(C)O
SMILES (Isomeric) C[C@H]1[C@@](C(=O)C2=CC(=C(C=C2[C@]1(C3=CC4=C(C=C3)OCO4)O)OC)OC)(C)O
InChI InChI=1S/C21H22O7/c1-11-20(2,23)19(22)13-8-16(25-3)17(26-4)9-14(13)21(11,24)12-5-6-15-18(7-12)28-10-27-15/h5-9,11,23-24H,10H2,1-4H3/t11-,20+,21-/m0/s1
InChI Key HFVJPDBHLXAZNH-JPXSGTFLSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C21H22O7
Molecular Weight 386.40 g/mol
Exact Mass 386.13655304 g/mol
Topological Polar Surface Area (TPSA) 94.40 Ų
XlogP 2.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-2,4-dihydroxy-6,7-dimethoxy-2,3-dimethyl-3H-naphthalen-1-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 98.40% 96.77%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.61% 91.11%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 95.17% 94.80%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.37% 86.33%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.11% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.04% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.00% 85.14%
CHEMBL2581 P07339 Cathepsin D 92.29% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.25% 95.56%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 88.76% 97.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.98% 89.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.81% 97.09%
CHEMBL4208 P20618 Proteasome component C5 86.13% 90.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.61% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.37% 92.62%
CHEMBL241 Q14432 Phosphodiesterase 3A 84.99% 92.94%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 84.98% 82.67%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 84.29% 96.86%
CHEMBL1937 Q92769 Histone deacetylase 2 83.59% 94.75%
CHEMBL2535 P11166 Glucose transporter 82.84% 98.75%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.72% 100.00%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.86% 90.24%
CHEMBL2413 P32246 C-C chemokine receptor type 1 80.33% 89.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.05% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Virola elongata

Cross-Links

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PubChem 14655056
LOTUS LTS0021476
wikiData Q105027563