Ankaraholide B

Details

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Internal ID f58c0432-6d4b-499c-b90b-d070eb013e9d
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (1R,3S,5E,7Z,11S,12S,13R,15S,17S,19S,23R,25S,27Z,29E,33S,34S,35R,37S,39R,41S)-13,15,35,37-tetrahydroxy-3,25-bis[[(2R,3R,4R,5S)-5-hydroxy-3,4-dimethoxyoxan-2-yl]oxy]-11,33-bis[(2S,3S,4S)-3-hydroxy-6-[(2S,4R,6S)-4-methoxy-6-methyloxan-2-yl]-4-methylhexan-2-yl]-17,39-dimethoxy-6,12,16,28,34-pentamethyl-10,32,45,46-tetraoxatricyclo[39.3.1.119,23]hexatetraconta-5,7,21,27,29,43-hexaene-9,31-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C91H154O28/c1-51-26-32-69(116-90-88(108-18)86(106-16)77(96)49-110-90)42-63-22-20-24-65(114-63)44-73(104-14)40-62(92)41-74(93)58(8)84(60(10)82(100)53(3)30-34-67-45-71(102-12)38-55(5)112-67)118-80(98)36-28-52(2)27-33-70(117-91-89(109-19)87(107-17)78(97)50-111-91)43-64-23-21-25-66(115-64)47-79(105-15)57(7)75(94)48-76(95)59(9)85(119-81(99)37-29-51)61(11)83(101)54(4)31-35-68-46-72(103-13)39-56(6)113-68/h20-23,26-29,36-37,53-79,82-97,100-101H,24-25,30-35,38-50H2,1-19H3/b36-28+,37-29-,51-26+,52-27-/t53-,54-,55-,56-,57?,58-,59-,60-,61-,62+,63-,64-,65-,66-,67-,68-,69-,70-,71+,72+,73+,74+,75-,76+,77-,78-,79-,82-,83-,84-,85-,86+,87+,88+,89+,90+,91+/m0/s1
InChI Key KMBIYPMGRFQUNL-FJJIQMLRSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C91H154O28
Molecular Weight 1696.20 g/mol
Exact Mass 1695.06266425 g/mol
Topological Polar Surface Area (TPSA) 362.00 Ų
XlogP 9.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ankaraholide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.45% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.67% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.56% 91.11%
CHEMBL2581 P07339 Cathepsin D 94.37% 98.95%
CHEMBL3401 O75469 Pregnane X receptor 93.12% 94.73%
CHEMBL230 P35354 Cyclooxygenase-2 92.52% 89.63%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.69% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.02% 97.09%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.89% 90.71%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.70% 91.07%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.04% 94.45%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.37% 99.23%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 84.11% 96.47%
CHEMBL4208 P20618 Proteasome component C5 84.11% 90.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.85% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.70% 89.00%
CHEMBL2996 Q05655 Protein kinase C delta 83.18% 97.79%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 82.39% 96.95%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683703
LOTUS LTS0092994
wikiData Q104202992