2alpha-Hydroxyjatropholone

Details

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Internal ID 08cb5311-ccce-4ba9-9e9a-0b6baa4afaea
Taxonomy Benzenoids > Indanes > Indanones
IUPAC Name (4R,10S,12R)-4,7-dihydroxy-4,8,11,11-tetramethyl-15-methylidenetetracyclo[7.6.0.02,6.010,12]pentadeca-1,6,8-trien-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H24O3/c1-9-6-7-12-16(19(12,3)4)14-10(2)17(21)11-8-20(5,23)18(22)15(11)13(9)14/h12,16,21,23H,1,6-8H2,2-5H3/t12-,16-,20-/m1/s1
InChI Key GXKSQESISBERSQ-CBLJQSSYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C20H24O3
Molecular Weight 312.40 g/mol
Exact Mass 312.17254462 g/mol
Topological Polar Surface Area (TPSA) 57.50 Ų
XlogP 3.60

Synonyms

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(4R,10S,12R)-4,7-dihydroxy-4,8,11,11-tetramethyl-15-methylidenetetracyclo[7.6.0.02,6.010,12]pentadeca-1,6,8-trien-3-one
RefChem:90041
2alpha-hydroxyjatropholone
1192839-16-9
CHEMBL1087936

2D Structure

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2D Structure of 2alpha-Hydroxyjatropholone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.51% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 92.39% 96.38%
CHEMBL1951 P21397 Monoamine oxidase A 90.37% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.97% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.85% 95.89%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 88.99% 91.79%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.37% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.24% 100.00%
CHEMBL4581 P52732 Kinesin-like protein 1 87.78% 93.18%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.58% 96.09%
CHEMBL1871 P10275 Androgen Receptor 84.65% 96.43%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.54% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.09% 94.45%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 84.01% 96.21%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.75% 93.03%
CHEMBL1929 P47989 Xanthine dehydrogenase 82.04% 96.12%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.82% 90.71%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.52% 92.94%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Jatropha integerrima

Cross-Links

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PubChem 44604948
LOTUS LTS0235334
wikiData Q105023156