Lonomycin B

Details

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Internal ID 9d162f26-23c5-4651-aced-b3f0e9d7724f
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Glycosyl compounds > C-glycosyl compounds
IUPAC Name (2S)-2-[(2S,3R,4S,5R,6R)-2-hydroxy-6-[(1S)-1-[(2S,5R,7S,8R,9R)-2-[(2R,5S)-5-[(2R,3S,4R,5R)-5-[(2S,3S,4S,5R,6S)-6-hydroxy-4-methoxy-3,5,6-trimethyloxan-2-yl]-4-methoxy-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]ethyl]-4-methoxy-3,5-dimethyloxan-2-yl]propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C44H76O14/c1-21-29(49-12)20-43(56-31(21)22(2)32-23(3)34(51-14)27(7)44(48,57-32)28(8)39(45)46)19-18-40(9,58-43)30-16-17-41(10,54-30)38-25(5)35(52-15)37(53-38)36-24(4)33(50-13)26(6)42(11,47)55-36/h21-38,47-48H,16-20H2,1-15H3,(H,45,46)/t21-,22-,23+,24+,25+,26-,27-,28-,29+,30-,31-,32+,33+,34+,35-,36+,37-,38-,40+,41+,42+,43-,44+/m1/s1
InChI Key BKZOUCVNTCLNFF-MPOKQCPUSA-N
Popularity 25 references in papers

Physical and Chemical Properties

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Molecular Formula C44H76O14
Molecular Weight 829.10 g/mol
Exact Mass 828.52350709 g/mol
Topological Polar Surface Area (TPSA) 170.00 Ų
XlogP 5.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Lonomycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.74% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.93% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.59% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.91% 97.14%
CHEMBL2581 P07339 Cathepsin D 91.43% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.31% 86.33%
CHEMBL340 P08684 Cytochrome P450 3A4 89.69% 91.19%
CHEMBL221 P23219 Cyclooxygenase-1 89.59% 90.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.98% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.54% 89.00%
CHEMBL2782 P35610 Acyl coenzyme A:cholesterol acyltransferase 1 84.63% 91.65%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.20% 96.95%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.89% 97.09%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.66% 95.89%
CHEMBL4302 P08183 P-glycoprotein 1 83.11% 92.98%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 83.06% 93.04%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.72% 99.23%
CHEMBL5255 O00206 Toll-like receptor 4 81.23% 92.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589135
LOTUS LTS0064856
wikiData Q104937853