27-Methoxylmilbemycin alpha31

Details

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Internal ID f03e310c-e9ee-4965-8d5b-4253b6688fb7
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (4S,5'S,6R,6'R,8R,10E,13R,14E)-6'-ethyl-21-hydroxy-18-methoxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-1(24),10,14,16,20,22-hexaene-6,2'-oxane]-2-one
SMILES (Canonical) CCC1C(CCC2(O1)CC3CC(O2)CC=C(CC(C=CC=C4C(OC5=C(C(=CC(=C45)C(=O)O3)C)O)OC)C)C)C
SMILES (Isomeric) CC[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/C[C@H](/C=C/C=C4C(OC5=C(C(=CC(=C45)C(=O)O3)C)O)OC)C)\C)C
InChI InChI=1S/C33H44O7/c1-7-27-21(4)13-14-33(40-27)18-24-17-23(39-33)12-11-20(3)15-19(2)9-8-10-25-28-26(31(35)37-24)16-22(5)29(34)30(28)38-32(25)36-6/h8-11,16,19,21,23-24,27,32,34H,7,12-15,17-18H2,1-6H3/b9-8+,20-11+,25-10?/t19-,21-,23+,24-,27+,32?,33+/m0/s1
InChI Key JWOMEKXEWNUTBW-MUTVBVKVSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C33H44O7
Molecular Weight 552.70 g/mol
Exact Mass 552.30870374 g/mol
Topological Polar Surface Area (TPSA) 83.40 Ų
XlogP 6.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 27-Methoxylmilbemycin alpha31

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.59% 91.11%
CHEMBL218 P21554 Cannabinoid CB1 receptor 96.22% 96.61%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.71% 86.33%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.36% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.30% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.27% 97.25%
CHEMBL2581 P07339 Cathepsin D 91.89% 98.95%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.56% 97.09%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 91.26% 94.80%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 90.52% 96.95%
CHEMBL3401 O75469 Pregnane X receptor 90.21% 94.73%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.44% 94.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.61% 89.00%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 88.42% 96.21%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 85.24% 97.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.72% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.28% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.16% 91.07%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.40% 92.62%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.77% 97.14%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.64% 82.38%
CHEMBL2073 P07947 Tyrosine-protein kinase YES 81.40% 83.14%
CHEMBL4530 P00488 Coagulation factor XIII 81.26% 96.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.66% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139591609
LOTUS LTS0126128
wikiData Q105136254