21-Oxopristimerine

Details

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Internal ID bddf4db0-a934-4cb2-ad7f-7f452d0510a3
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Triterpenoids
IUPAC Name methyl (2S,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-3,11-dioxo-4,5,6,13,14,14b-hexahydro-1H-picene-2-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H38O5/c1-17-18-8-9-21-27(3,19(18)14-20(31)24(17)33)11-13-30(6)22-15-28(4,25(34)35-7)23(32)16-26(22,2)10-12-29(21,30)5/h8-9,14,22,33H,10-13,15-16H2,1-7H3/t22-,26+,27+,28+,29-,30+/m1/s1
InChI Key MTZSYUQVIKIBDX-KLGNMXTRSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C30H38O5
Molecular Weight 478.60 g/mol
Exact Mass 478.27192431 g/mol
Topological Polar Surface Area (TPSA) 80.70 Ų
XlogP 5.30

Synonyms

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RefChem:89672
methyl (2S,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-3,11-dioxo-4,5,6,13,14,14b-hexahydro-1H-picene-2-carboxylate
CHEMBL1651337
SCHEMBL30271479

2D Structure

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2D Structure of 21-Oxopristimerine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.81% 91.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.21% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.20% 94.45%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.65% 93.03%
CHEMBL1937 Q92769 Histone deacetylase 2 91.31% 94.75%
CHEMBL3746 P80365 11-beta-hydroxysteroid dehydrogenase 2 87.93% 94.78%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.54% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.31% 95.56%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 83.87% 82.69%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.52% 91.07%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.08% 94.00%
CHEMBL2581 P07339 Cathepsin D 82.45% 98.95%
CHEMBL340 P08684 Cytochrome P450 3A4 82.41% 91.19%
CHEMBL241 Q14432 Phosphodiesterase 3A 82.30% 92.94%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Maytenus retusa

Cross-Links

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PubChem 50907761
NPASS NPC777
ChEMBL CHEMBL1651337
LOTUS LTS0073737
wikiData Q105172004