20-hydroxyrifamycin S

Details

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Internal ID 6438ab6c-24c4-4617-b410-a2218df043cf
Taxonomy Phenylpropanoids and polyketides > Macrolactams
IUPAC Name [(7S,9E,11S,12R,13S,14R,15R,16S,17R,18R,19E,21E)-2,15,17,18-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaen-13-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C37H45NO13/c1-16-11-10-13-36(7,47)33(44)20(5)28(41)18(3)31(50-21(6)39)17(2)24(48-9)12-14-49-37(8)34(45)27-25-23(40)15-22(38-35(16)46)30(43)26(25)29(42)19(4)32(27)51-37/h10-15,17-18,20,24,28,31,33,41-42,44,47H,1-9H3,(H,38,46)/b13-10+,14-12+,16-11+/t17-,18-,20+,24+,28+,31-,33-,36-,37+/m1/s1
InChI Key JNENPBGVIMPKJY-AKRCJVEDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C37H45NO13
Molecular Weight 711.80 g/mol
Exact Mass 711.28909049 g/mol
Topological Polar Surface Area (TPSA) 215.00 Ų
XlogP 2.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 20-hydroxyrifamycin S

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.58% 85.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.42% 91.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 96.57% 89.00%
CHEMBL2581 P07339 Cathepsin D 96.13% 98.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 95.48% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.51% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.52% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.79% 95.56%
CHEMBL3401 O75469 Pregnane X receptor 91.34% 94.73%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.52% 94.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 88.16% 96.77%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 84.33% 96.67%
CHEMBL3922 P50579 Methionine aminopeptidase 2 82.48% 97.28%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.86% 91.07%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.11% 86.33%
CHEMBL3864 Q06124 Protein-tyrosine phosphatase 2C 80.56% 94.42%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683147
LOTUS LTS0035588
wikiData Q105131867