2-methoxy-1-(9H-pyrido(3,4-b)indol-1-yl)ethanone

Details

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Internal ID b24e7a32-022f-4376-b50e-1c4c403d3555
Taxonomy Alkaloids and derivatives > Harmala alkaloids
IUPAC Name 2-methoxy-1-(9H-pyrido[3,4-b]indol-1-yl)ethanone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C14H12N2O2/c1-18-8-12(17)14-13-10(6-7-15-14)9-4-2-3-5-11(9)16-13/h2-7,16H,8H2,1H3
InChI Key KGXNMZDNPKYEHN-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C14H12N2O2
Molecular Weight 240.26 g/mol
Exact Mass 240.089877630 g/mol
Topological Polar Surface Area (TPSA) 55.00 Ų
XlogP 2.20

Synonyms

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123520-94-5
2-methoxy-1-(9H-pyrido[3,4-b]indol-1-yl)ethanone
DTXSID00154032

2D Structure

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2D Structure of 2-methoxy-1-(9H-pyrido(3,4-b)indol-1-yl)ethanone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.02% 96.09%
CHEMBL255 P29275 Adenosine A2b receptor 93.09% 98.59%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.68% 91.11%
CHEMBL2581 P07339 Cathepsin D 90.39% 98.95%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 89.50% 96.47%
CHEMBL4040 P28482 MAP kinase ERK2 89.46% 83.82%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 89.18% 92.67%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.74% 94.00%
CHEMBL1781 P11387 DNA topoisomerase I 85.99% 97.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.91% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 85.83% 85.14%
CHEMBL2535 P11166 Glucose transporter 85.26% 98.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.06% 89.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.18% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.14% 99.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.74% 86.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.57% 99.23%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 83.34% 94.62%
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 83.26% 93.24%
CHEMBL4208 P20618 Proteasome component C5 82.86% 90.00%
CHEMBL2885 P07451 Carbonic anhydrase III 81.61% 87.45%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 80.26% 91.71%
CHEMBL3401 O75469 Pregnane X receptor 80.26% 94.73%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.10% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Arenaria kansuensis

Cross-Links

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PubChem 183645
LOTUS LTS0075935
wikiData Q83021136