1H-Pyrrole-2,5-dicarboxylic acid, 3,4-di-1H-indol-3-yl-, dimethyl ester

Details

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Internal ID 7e872371-f732-4559-bbe0-a7820d3fc2ab
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles
IUPAC Name dimethyl 3,4-bis(1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylate
SMILES (Canonical) COC(=O)C1=C(C(=C(N1)C(=O)OC)C2=CNC3=CC=CC=C32)C4=CNC5=CC=CC=C54
SMILES (Isomeric) COC(=O)C1=C(C(=C(N1)C(=O)OC)C2=CNC3=CC=CC=C32)C4=CNC5=CC=CC=C54
InChI InChI=1S/C24H19N3O4/c1-30-23(28)21-19(15-11-25-17-9-5-3-7-13(15)17)20(22(27-21)24(29)31-2)16-12-26-18-10-6-4-8-14(16)18/h3-12,25-27H,1-2H3
InChI Key DKTWEIRHZXHFQB-UHFFFAOYSA-N
Popularity 7 references in papers

Physical and Chemical Properties

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Molecular Formula C24H19N3O4
Molecular Weight 413.40 g/mol
Exact Mass 413.13755610 g/mol
Topological Polar Surface Area (TPSA) 100.00 Ų
XlogP 4.60

Synonyms

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150044-77-2
1H-Pyrrole-2,5-dicarboxylic acid, 3,4-di-1H-indol-3-yl-, dimethyl ester
CHEMBL371472
SCHEMBL12658123
DTXSID80452826

2D Structure

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2D Structure of 1H-Pyrrole-2,5-dicarboxylic acid, 3,4-di-1H-indol-3-yl-, dimethyl ester

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.44% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.24% 96.09%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 93.80% 92.67%
CHEMBL2581 P07339 Cathepsin D 93.24% 98.95%
CHEMBL2535 P11166 Glucose transporter 92.37% 98.75%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 86.54% 81.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.51% 95.56%
CHEMBL4208 P20618 Proteasome component C5 84.54% 90.00%
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 84.22% 93.24%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.66% 99.23%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.14% 93.03%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.78% 85.14%
CHEMBL2002 P12268 Inosine-5'-monophosphate dehydrogenase 2 82.66% 98.21%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.90% 94.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 81.77% 95.56%
CHEMBL5028 O14672 ADAM10 81.57% 97.50%
CHEMBL3401 O75469 Pregnane X receptor 80.86% 94.73%
CHEMBL255 P29275 Adenosine A2b receptor 80.70% 98.59%
CHEMBL1951 P21397 Monoamine oxidase A 80.68% 91.49%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11037060
LOTUS LTS0222967
wikiData Q77571330