FR220897

Details

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Internal ID cbc6eb93-9712-4a38-bb42-33e3cad7de09
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Oligopeptides
IUPAC Name [4-[2-[3-(3-amino-1-hydroxy-3-oxopropyl)-18-(hexadecanoylamino)-11,20,21,25-tetrahydroxy-15-(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-6-yl]-2-hydroxyethyl]-2-hydroxyphenyl] hydrogen sulfate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C51H82N8O20S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-39(67)53-31-23-36(65)47(71)57-49(73)43-44(68)27(2)25-59(43)51(75)42(35(64)24-38(52)66)56-48(72)41(34(63)21-29-18-19-37(33(62)20-29)79-80(76,77)78)55-46(70)32-22-30(61)26-58(32)50(74)40(28(3)60)54-45(31)69/h18-20,27-28,30-32,34-36,40-44,47,60-65,68,71H,4-17,21-26H2,1-3H3,(H2,52,66)(H,53,67)(H,54,69)(H,55,70)(H,56,72)(H,57,73)(H,76,77,78)
InChI Key GFEXQVWXQYCVIC-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C51H82N8O20S
Molecular Weight 1159.30 g/mol
Exact Mass 1158.53660821 g/mol
Topological Polar Surface Area (TPSA) 463.00 Ų
XlogP 1.60

Synonyms

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[4-[2-[3-(3-Amino-1-hydroxy-3-oxopropyl)-18-(hexadecanoylamino)-11,20,21,25-tetrahydroxy-15-(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-6-yl]-2-hydroxyethyl]-2-hydroxyphenyl] hydrogen sulfate

2D Structure

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2D Structure of FR220897

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.81% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.72% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.19% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 97.01% 99.17%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 96.84% 90.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 96.04% 97.09%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 94.46% 92.08%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.37% 91.11%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.92% 82.69%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.32% 95.56%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 90.40% 92.86%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 89.98% 100.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 89.44% 95.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 89.41% 91.03%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 89.25% 96.90%
CHEMBL255 P29275 Adenosine A2b receptor 88.97% 98.59%
CHEMBL340 P08684 Cytochrome P450 3A4 88.83% 91.19%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.69% 95.89%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 88.39% 92.88%
CHEMBL2535 P11166 Glucose transporter 88.24% 98.75%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 86.88% 95.89%
CHEMBL218 P21554 Cannabinoid CB1 receptor 86.15% 96.61%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 85.93% 82.38%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 85.83% 96.95%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 84.66% 93.03%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 83.79% 97.64%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 83.74% 96.25%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.59% 97.14%
CHEMBL1075162 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor 83.36% 80.33%
CHEMBL4588 P22894 Matrix metalloproteinase 8 83.14% 94.66%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.13% 94.33%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.73% 95.50%
CHEMBL3437 Q16853 Amine oxidase, copper containing 82.41% 94.00%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 82.32% 96.00%
CHEMBL2413 P32246 C-C chemokine receptor type 1 82.05% 89.50%
CHEMBL5255 O00206 Toll-like receptor 4 81.87% 92.50%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.34% 96.47%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 80.97% 97.21%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 80.65% 96.38%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.16% 96.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.06% 90.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 9898376
LOTUS LTS0074930
wikiData Q75057191