18-oxonapyradiomycin A1

Details

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Internal ID 20a0f3fb-1b81-4d8f-82da-1a2d74519c26
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Quinone and hydroquinone lipids > Vitamin K compounds > Menaquinones
IUPAC Name 8-[(3R,4aR,10aS)-3,4a-dichloro-6,8-dihydroxy-2,2-dimethyl-5,10-dioxo-3,4-dihydrobenzo[g]chromen-10a-yl]-2,6-dimethylocta-2,6-dienal
SMILES (Canonical) CC(=CCC12C(=O)C3=C(C(=CC(=C3)O)O)C(=O)C1(CC(C(O2)(C)C)Cl)Cl)CCC=C(C)C=O
SMILES (Isomeric) CC(=CC[C@]12C(=O)C3=C(C(=CC(=C3)O)O)C(=O)[C@]1(C[C@H](C(O2)(C)C)Cl)Cl)CCC=C(C)C=O
InChI InChI=1S/C25H28Cl2O6/c1-14(6-5-7-15(2)13-28)8-9-25-21(31)17-10-16(29)11-18(30)20(17)22(32)24(25,27)12-19(26)23(3,4)33-25/h7-8,10-11,13,19,29-30H,5-6,9,12H2,1-4H3/t19-,24+,25+/m1/s1
InChI Key FPOOHFGLFKYUON-NGXZDTIWSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C25H28Cl2O6
Molecular Weight 495.40 g/mol
Exact Mass 494.1262940 g/mol
Topological Polar Surface Area (TPSA) 101.00 Ų
XlogP 5.20

Synonyms

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8-[(3R,4aR,10aS)-3,4a-dichloro-6,8-dihydroxy-2,2-dimethyl-5,10-dioxo-3,4-dihydrobenzo[g]chromen-10a-yl]-2,6-dimethylocta-2,6-dienal
8-((3R,4aR,10aS)-3,4a-dichloro-6,8-dihydroxy-2,2-dimethyl-5,10-dioxo-3,4-dihydrobenzo(g)chromen-10a-yl)-2,6-dimethylocta-2,6-dienal
RefChem:79409
1012860-15-9
CHEBI:216766

2D Structure

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2D Structure of 18-oxonapyradiomycin A1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.67% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 96.67% 91.49%
CHEMBL2581 P07339 Cathepsin D 94.53% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.35% 96.09%
CHEMBL4208 P20618 Proteasome component C5 93.88% 90.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.88% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.25% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.64% 86.33%
CHEMBL2039 P27338 Monoamine oxidase B 90.59% 92.51%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.39% 97.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 89.50% 99.17%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.45% 94.45%
CHEMBL3401 O75469 Pregnane X receptor 89.21% 94.73%
CHEMBL3492 P49721 Proteasome Macropain subunit 88.31% 90.24%
CHEMBL1937 Q92769 Histone deacetylase 2 88.17% 94.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.08% 95.89%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 85.88% 92.68%
CHEMBL1929 P47989 Xanthine dehydrogenase 84.99% 96.12%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 84.78% 89.34%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.70% 96.95%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 84.43% 96.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.01% 92.94%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 82.00% 85.11%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.86% 95.50%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 80.05% 93.40%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139586143
LOTUS LTS0076516
wikiData Q77499796