(17S,23S)-17,23-epoxy-3beta,15alpha-dihydroxy-7,11-dioxo-5alpha-lanosta-8-en-26,23-olide

Details

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Internal ID e35450dc-295b-4391-ba86-342cc2b2d832
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Steroid lactones > Withanolides and derivatives
IUPAC Name
SMILES (Canonical) CC1CC2(CC(C3(O2)CC(C4(C3(CC(=O)C5=C4C(=O)CC6C5(CCC(C6(C)C)O)C)C)C)O)C)OC1=O
SMILES (Isomeric) C[C@@H]1C[C@]2(C[C@H]([C@@]3(O2)C[C@@H]([C@@]4([C@@]3(CC(=O)C5=C4C(=O)C[C@@H]6[C@@]5(CC[C@@H](C6(C)C)O)C)C)C)O)C)OC1=O
InChI InChI=1S/C30H42O7/c1-15-11-29(36-24(15)35)12-16(2)30(37-29)14-21(34)28(7)23-17(31)10-19-25(3,4)20(33)8-9-26(19,5)22(23)18(32)13-27(28,30)6/h15-16,19-21,33-34H,8-14H2,1-7H3/t15-,16-,19+,20+,21+,26+,27+,28+,29+,30+/m1/s1
InChI Key GHTXJUWCAZBSKK-BZDHVDRSSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C30H42O7
Molecular Weight 514.60 g/mol
Exact Mass 514.29305367 g/mol
Topological Polar Surface Area (TPSA) 110.00 Ų
XlogP 3.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (17S,23S)-17,23-epoxy-3beta,15alpha-dihydroxy-7,11-dioxo-5alpha-lanosta-8-en-26,23-olide

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.43% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.73% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 90.49% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.18% 97.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.61% 89.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 89.38% 100.00%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 88.72% 85.30%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 87.83% 96.77%
CHEMBL2581 P07339 Cathepsin D 87.78% 98.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.07% 99.23%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 84.45% 86.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.62% 92.88%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 83.19% 96.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.00% 92.94%
CHEMBL1902 P62942 FK506-binding protein 1A 81.96% 97.05%
CHEMBL253 P34972 Cannabinoid CB2 receptor 80.96% 97.25%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 80.16% 89.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684143
LOTUS LTS0057965
wikiData Q105008720