isopseudolarifuroic acid B

Details

Top
Internal ID 0035ec25-b228-437b-99f9-435678c71b13
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Bile acids, alcohols and derivatives > Hydroxy bile acids, alcohols and derivatives > Monohydroxy bile acids, alcohols and derivatives
IUPAC Name (3R)-3-[(3R,5R,9S,10R,13S,17S)-3-hydroxy-4,4,10,13,17-pentamethyl-2,3,5,6,9,11,12,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]butanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H40O3/c1-16(15-22(28)29)25(5)13-10-19-17-7-8-20-23(2,3)21(27)11-12-24(20,4)18(17)9-14-26(19,25)6/h7,10,16,18,20-21,27H,8-9,11-15H2,1-6H3,(H,28,29)/t16-,18-,20+,21-,24-,25+,26-/m1/s1
InChI Key DNSLKYSOTQONTJ-XIJCTPQQSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C26H40O3
Molecular Weight 400.60 g/mol
Exact Mass 400.29774513 g/mol
Topological Polar Surface Area (TPSA) 57.50 Ų
XlogP 5.50

Synonyms

Top
RefChem:923776
(3R)-3-((3R,5R,9S,10R,13S,17S)-3-hydroxy-4,4,10,13,17-pentamethyl-2,3,5,6,9,11,12,16-octahydro-1H-cyclopenta(a)phenanthren-17-yl)butanoic acid

2D Structure

Top
2D Structure of isopseudolarifuroic acid B

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL221 P23219 Cyclooxygenase-1 97.76% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.74% 96.09%
CHEMBL2581 P07339 Cathepsin D 96.10% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.59% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.10% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.53% 97.25%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 86.67% 94.23%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.28% 100.00%
CHEMBL4040 P28482 MAP kinase ERK2 84.79% 83.82%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.56% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.81% 100.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.00% 95.56%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.59% 93.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.04% 95.89%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Larix kaempferi

Cross-Links

Top
PubChem 101147487
LOTUS LTS0054331
wikiData Q104985717