Tecleanthine

Details

• Internal ID: 4c6b4699-a629-4444-8371-3b15a99abfcd
• Taxonomy: Organoheterocyclic compounds > Quinolines and derivatives > Benzoquinolines > Acridines > Acridones
• IUPAC Name: 6,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
• InChI: InChI=1S/C17H15NO5/c1-18-10-7-12-16(23-8-22-12)17(21-3)13(10)15(19)9-5-4-6-11(20-2)14(9)18/h4-7H,8H2,1-3H3
• InChI Key: QYWWGVQKWKTLMU-UHFFFAOYSA-N
• Popularity: 5 references in papers

Physical and Chemical Properties

• Molecular Formula: C₁₇H₁₅NO₅
• Molecular Weight: 313.30 g/mol
• Exact Mass: 313.09502258 g/mol
• Topological Polar Surface Area (TPSA): 57.20 Ų
• XlogP: 2.90

Synonyms

• 6,11-dimethoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
• 6,11-dimethoxy-5-methyl-(1,3)dioxolo(4,5-b)acridin-10-one
• RefChem:187683
• 24966-05-0
• Tecleanthin
• 1,3-Dioxolo[4,5-b]acridin-10(5H)-one, 6,11-dimethoxy-5-methyl-
• CHEMBL455629
• QYWWGVQKWKTLMU-UHFFFAOYSA-N
• 6,11-Dimethoxy-5-methyl[1,3]dioxolo[4,5-b]acridin-10(5H)-one #

2D Structure

ADMET Properties (via admetSAR 2)

Target	Value	Probability (raw)	Probability (%)
No predicted properties yet!

Targets

Proven Targets:

No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID	UniProt ID	Name	Probability	Model accuracy
CHEMBL3108638	O15164	Transcription intermediary factor 1-alpha	98.45%	95.56%
CHEMBL4303	P08238	Heat shock protein HSP 90-beta	98.04%	96.77%
CHEMBL3192	Q9BY41	Histone deacetylase 8	97.94%	93.99%
CHEMBL2581	P07339	Cathepsin D	96.10%	98.95%
CHEMBL3251	P19838	Nuclear factor NF-kappa-B p105 subunit	95.18%	96.09%
CHEMBL1293249	Q13887	Kruppel-like factor 5	94.96%	86.33%
CHEMBL2635	P51452	Dual specificity protein phosphatase 3	93.89%	94.00%
CHEMBL1806	P11388	DNA topoisomerase II alpha	93.14%	89.00%
CHEMBL2535	P11166	Glucose transporter	92.60%	98.75%
CHEMBL2373	P21730	C5a anaphylatoxin chemotactic receptor	91.18%	92.62%
CHEMBL4261	Q16665	Hypoxia-inducible factor 1 alpha	90.50%	85.14%
CHEMBL1075094	Q16236	Nuclear factor erythroid 2-related factor 2	88.75%	96.00%
CHEMBL5619	P27695	DNA-(apurinic or apyrimidinic site) lyase	86.53%	91.11%
CHEMBL3038477	P67870	Casein kinase II alpha/beta	85.29%	99.23%
CHEMBL2146302	O94925	Glutaminase kidney isoform, mitochondrial	84.78%	100.00%
CHEMBL4478	Q00975	Voltage-gated N-type calcium channel alpha-1B subunit	83.06%	97.14%
CHEMBL225	P28335	Serotonin 2c (5-HT2c) receptor	82.75%	89.62%
CHEMBL4306	P22460	Voltage-gated potassium channel subunit Kv1.5	82.46%	94.03%
CHEMBL4225	P49760	Dual specificity protein kinase CLK2	82.07%	80.96%
CHEMBL2717	Q9HCR9	Phosphodiesterase 11A	81.46%	85.00%

Plants that contains it

• Vepris boiviniana
• Vepris natalensis
• Vepris trichocarpa

Cross-Links

• PubChem: 628642
• LOTUS: LTS0101614
• wikiData: Q105231015