(12bR)-5-hydroxy-4,12b-dimethyl-1,2-dihydrobenzo[a]anthracene-6,8,11-trione
| Internal ID | c03b1cd2-c7f4-49e3-a6e5-0ae414f57268 |
| Taxonomy | Lipids and lipid-like molecules > Prenol lipids > Diterpenoids |
| IUPAC Name | (12bR)-5-hydroxy-4,12b-dimethyl-1,2-dihydrobenzo[a]anthracene-6,8,11-trione |
| SMILES (Canonical) | |
| SMILES (Isomeric) | |
| InChI | InChI=1S/C20H16O4/c1-10-4-3-7-20(2)14-9-12-11(15(21)5-6-16(12)22)8-13(14)18(23)19(24)17(10)20/h4-6,8-9,24H,3,7H2,1-2H3/t20-/m1/s1 |
| InChI Key | QDENTZCNQRGGAZ-HXUWFJFHSA-N |
| Popularity | 2 references in papers |
| Molecular Formula | C20H16O4 |
| Molecular Weight | 320.30 g/mol |
| Exact Mass | 320.10485899 g/mol |
| Topological Polar Surface Area (TPSA) | 71.40 Ų |
| XlogP | 2.80 |
| There are no found synonyms. |
![2D Structure of (12bR)-5-hydroxy-4,12b-dimethyl-1,2-dihydrobenzo[a]anthracene-6,8,11-trione](https://plantaedb.com/storage/docs/compounds/2023/11/12br-5-hydroxy-412b-dimethyl-12-dihydrobenzoaanthracene-6811-trione.jpg "2D Structure of (12bR)-5-hydroxy-4,12b-dimethyl-1,2-dihydrobenzo[a]anthracene-6,8,11-trione")
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| CHEMBL2094108 | P49354 | Protein farnesyltransferase |
410 nM |
IC50 |
via Super-PRED
|
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 95.18% | 91.11% |
| CHEMBL1937 | Q92769 | Histone deacetylase 2 | 92.82% | 94.75% |
| CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 90.69% | 95.56% |
| CHEMBL2581 | P07339 | Cathepsin D | 89.86% | 98.95% |
| CHEMBL2378 | P30307 | Dual specificity phosphatase Cdc25C | 89.22% | 96.67% |
| CHEMBL4208 | P20618 | Proteasome component C5 | 89.11% | 90.00% |
| CHEMBL5697 | Q9GZT9 | Egl nine homolog 1 | 88.67% | 93.40% |
| CHEMBL1806 | P11388 | DNA topoisomerase II alpha | 87.13% | 89.00% |
| CHEMBL1951 | P21397 | Monoamine oxidase A | 86.65% | 91.49% |
| CHEMBL1293249 | Q13887 | Kruppel-like factor 5 | 85.70% | 86.33% |
| CHEMBL2007 | P16234 | Platelet-derived growth factor receptor alpha | 83.52% | 91.07% |
| CHEMBL3492 | P49721 | Proteasome Macropain subunit | 83.38% | 90.24% |
| CHEMBL4685 | P14902 | Indoleamine 2,3-dioxygenase | 83.31% | 96.38% |
| CHEMBL3038477 | P67870 | Casein kinase II alpha/beta | 83.14% | 99.23% |
| CHEMBL3192 | Q9BY41 | Histone deacetylase 8 | 82.54% | 93.99% |
| CHEMBL2635 | P51452 | Dual specificity protein phosphatase 3 | 82.46% | 94.00% |
| CHEMBL241 | Q14432 | Phosphodiesterase 3A | 82.14% | 92.94% |
| CHEMBL1907600 | Q00535 | Cyclin-dependent kinase 5/CDK5 activator 1 | 81.87% | 93.03% |
| CHEMBL1994 | P08235 | Mineralocorticoid receptor | 81.16% | 100.00% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
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| There are no matching plants. |
| PubChem | 162930730 |
| LOTUS | LTS0048797 |
| wikiData | Q105218790 |