12-Dihydrodalbinol

Details

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Internal ID ab6bb660-9e25-42c9-8cea-23a72e6760c0
Taxonomy Phenylpropanoids and polyketides > Isoflavonoids > Rotenoids > Rotenones
IUPAC Name 6-(3-hydroxyprop-1-en-2-yl)-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaene-12,13-diol
SMILES (Canonical) COC1=C(C=C2C(=C1)C3(C(CO2)OC4=C(C3O)C=CC5=C4CC(O5)C(=C)CO)O)OC
SMILES (Isomeric) COC1=C(C=C2C(=C1)C3(C(CO2)OC4=C(C3O)C=CC5=C4CC(O5)C(=C)CO)O)OC
InChI InChI=1S/C23H24O8/c1-11(9-24)16-6-13-15(30-16)5-4-12-21(13)31-20-10-29-17-8-19(28-3)18(27-2)7-14(17)23(20,26)22(12)25/h4-5,7-8,16,20,22,24-26H,1,6,9-10H2,2-3H3
InChI Key NCYYYSSAGZJHHG-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C23H24O8
Molecular Weight 428.40 g/mol
Exact Mass 428.14711772 g/mol
Topological Polar Surface Area (TPSA) 107.00 Ų
XlogP 1.30

Synonyms

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CHEBI:191917
LMPK12060042
6-(3-hydroxyprop-1-en-2-yl)-16,17-dimethoxy-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaene-12,13-diol

2D Structure

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2D Structure of 12-Dihydrodalbinol

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.10% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.22% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.53% 94.45%
CHEMBL4040 P28482 MAP kinase ERK2 94.11% 83.82%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.90% 95.89%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 91.77% 94.80%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.73% 86.33%
CHEMBL2581 P07339 Cathepsin D 90.63% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 89.95% 85.14%
CHEMBL1994 P08235 Mineralocorticoid receptor 87.55% 100.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 86.50% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.54% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.91% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 83.58% 97.25%
CHEMBL5555 O00767 Acyl-CoA desaturase 83.23% 97.50%
CHEMBL2535 P11166 Glucose transporter 81.95% 98.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.77% 89.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 81.23% 93.99%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.16% 97.14%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 80.96% 94.03%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.58% 92.94%
CHEMBL4355 O14976 Serine/threonine-protein kinase GAK 80.30% 89.32%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.10% 99.17%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44257413
LOTUS LTS0074210
wikiData Q105177445