1,11-dideacetyl pyripyropene A

Details

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Internal ID dd40a858-c4a9-4e50-92b7-df2f4c08e134
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Hydroxysteroids > 1-hydroxysteroids
IUPAC Name [(1S,2S,5S,6R,7R,9S,10S,18R)-5,18-dihydroxy-6-(hydroxymethyl)-2,6,10-trimethyl-16-oxo-14-pyridin-3-yl-11,15-dioxatetracyclo[8.8.0.02,7.012,17]octadeca-12(17),13-dien-9-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H33NO8/c1-14(30)34-20-11-18-25(2,8-7-19(31)26(18,3)13-29)23-22(32)21-17(36-27(20,23)4)10-16(35-24(21)33)15-6-5-9-28-12-15/h5-6,9-10,12,18-20,22-23,29,31-32H,7-8,11,13H2,1-4H3/t18-,19+,20+,22+,23-,25+,26+,27-/m1/s1
InChI Key VEVRHRCWDFOGJW-ODHUSUJMSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C27H33NO8
Molecular Weight 499.60 g/mol
Exact Mass 499.22061701 g/mol
Topological Polar Surface Area (TPSA) 135.00 Ų
XlogP 1.90

Synonyms

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[(1S,2S,5S,6R,7R,9S,10S,18R)-5,18-dihydroxy-6-(hydroxymethyl)-2,6,10-trimethyl-16-oxo-14-pyridin-3-yl-11,15-dioxatetracyclo[8.8.0.02,7.012,17]octadeca-12(17),13-dien-9-yl] acetate
((1S,2S,5S,6R,7R,9S,10S,18R)-5,18-dihydroxy-6-(hydroxymethyl)-2,6,10-trimethyl-16-oxo-14-pyridin-3-yl-11,15-dioxatetracyclo(8.8.0.02,7.012,17)octadeca-12(17),13-dien-9-yl) acetate
RefChem:71177
(5AS,6S,7ar,8R,9S,11as,11BS,12R)-9,12-dihydroxy-8-(hydroxymethyl)-5a,8,11a-trimethyl-1-oxo-3-(pyridin-3-yl)-1,5a,6,7,7a,8,9,10,11,11a,11b,12-dodecahydro-2,5-dioxatetraphen-6-yl acetic acid
CHEBI:216076

2D Structure

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2D Structure of 1,11-dideacetyl pyripyropene A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4465 O75908 Acyl coenzyme A:cholesterol acyltransferase 2 97.80% 100.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 97.53% 86.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.00% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 96.56% 83.82%
CHEMBL2581 P07339 Cathepsin D 94.67% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.32% 89.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.03% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.02% 97.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.79% 85.14%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 91.79% 81.11%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.83% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.23% 95.89%
CHEMBL5028 O14672 ADAM10 85.87% 97.50%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 85.81% 96.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.71% 100.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.57% 92.62%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 81.74% 85.30%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.79% 99.17%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10649029
LOTUS LTS0240634
wikiData Q105284887