1-Hydroxy-3,4,5-trimethoxyxanthone

Details

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Internal ID 503d98af-52ff-4436-9e80-73b06fabc791
Taxonomy Organoheterocyclic compounds > Benzopyrans > 1-benzopyrans > Xanthones
IUPAC Name 1-hydroxy-3,4,5-trimethoxyxanthen-9-one
SMILES (Canonical) COC1=CC=CC2=C1OC3=C(C2=O)C(=CC(=C3OC)OC)O
SMILES (Isomeric) COC1=CC=CC2=C1OC3=C(C2=O)C(=CC(=C3OC)OC)O
InChI InChI=1S/C16H14O6/c1-19-10-6-4-5-8-13(18)12-9(17)7-11(20-2)15(21-3)16(12)22-14(8)10/h4-7,17H,1-3H3
InChI Key VXTZMXABRBBPJM-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C16H14O6
Molecular Weight 302.28 g/mol
Exact Mass 302.07903816 g/mol
Topological Polar Surface Area (TPSA) 74.20 Ų
XlogP 3.10

Synonyms

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23251-63-0
20848-59-3
1-HYDROXY-3,4,5-TRIMETHOXYXANTHEN-9-ONE
9H-Xanthen-9-one,1-hydroxy-3,4,7-trimethoxy-
9H-Xanthen-9-one, 1-hydroxy-3,4,5-trimethoxy-

2D Structure

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2D Structure of 1-Hydroxy-3,4,5-trimethoxyxanthone

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.94% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.35% 95.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 95.55% 93.99%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.97% 94.00%
CHEMBL2535 P11166 Glucose transporter 92.81% 98.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.74% 89.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.13% 86.33%
CHEMBL2581 P07339 Cathepsin D 89.66% 98.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.09% 99.23%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 86.20% 99.15%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.91% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.75% 99.17%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 84.49% 93.65%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 83.35% 85.14%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.81% 95.50%
CHEMBL1255126 O15151 Protein Mdm4 82.73% 90.20%
CHEMBL3401 O75469 Pregnane X receptor 82.47% 94.73%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 81.85% 94.03%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.34% 92.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Garcinia dulcis
Lomatogonium carinthiacum

Cross-Links

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PubChem 72944463
LOTUS LTS0195967
wikiData Q105298762