1-Hydroxy-2-oxopomolic acid

Details

Top
Internal ID a66c9019-3726-48bf-b12d-ee93b62f7aa9
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Triterpenoids
IUPAC Name (1R,2R,4aS,6aS,6aS,6bR,8aS,10R,12S,12aR,14bS)-1,10,12-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-11-oxo-3,4,5,6,6a,7,8,8a,10,12,13,14b-dodecahydro-2H-picene-4a-carboxylic acid
SMILES (Canonical) CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(C(C(=O)C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O
SMILES (Isomeric) C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4([C@@H](C(=O)[C@@H](C5(C)C)O)O)C)C)[C@@H]2[C@]1(C)O)C)C(=O)O
InChI InChI=1S/C30H46O6/c1-16-10-13-30(24(34)35)15-14-26(4)17(21(30)29(16,7)36)8-9-19-27(26,5)12-11-18-25(2,3)22(32)20(31)23(33)28(18,19)6/h8,16,18-19,21-23,32-33,36H,9-15H2,1-7H3,(H,34,35)/t16-,18+,19+,21-,22+,23-,26-,27-,28+,29-,30+/m1/s1
InChI Key VBLIMTVKFVIDFU-PAZRJNPVSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C30H46O6
Molecular Weight 502.70 g/mol
Exact Mass 502.32943918 g/mol
Topological Polar Surface Area (TPSA) 115.00 Ų
XlogP 4.40

Synonyms

Top
217466-37-0
1beta-Hydroxy-2-oxopomolic acid
(1R,2R,4aS,6aS,6aS,6bR,8aS,10R,12S,12aR,14bS)-1,10,12-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-11-oxo-3,4,5,6,6a,7,8,8a,10,12,13,14b-dodecahydro-2H-picene-4a-carboxylic acid
CHEMBL461068
orb1683980
VBLIMTVKFVIDFU-PAZRJNPVSA-
HY-N1626
AKOS032961715
FS-9573
DA-59928
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

Top
2D Structure of 1-Hydroxy-2-oxopomolic acid

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.67% 95.56%
CHEMBL2581 P07339 Cathepsin D 92.11% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.83% 91.11%
CHEMBL340 P08684 Cytochrome P450 3A4 87.25% 91.19%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.23% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.16% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.97% 93.03%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 85.90% 82.69%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 85.36% 96.77%
CHEMBL221 P23219 Cyclooxygenase-1 85.09% 90.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.98% 93.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.13% 99.23%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.53% 92.94%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.22% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.36% 94.45%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Eriobotrya deflexa

Cross-Links

Top
PubChem 10625284
NPASS NPC118964
ChEMBL CHEMBL461068
LOTUS LTS0208525
wikiData Q105283337