1-(2-Hydroxy-3,4,6-trimethoxyphenyl)-3-phenylprop-2-en-1-one
| Internal ID | 82a2e1d3-4b52-4df7-920b-94ce4ddf3df6 |
| Taxonomy | Phenylpropanoids and polyketides > Linear 1,3-diarylpropanoids > Chalcones and dihydrochalcones > 2-Hydroxychalcones |
| IUPAC Name | 1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-phenylprop-2-en-1-one |
| SMILES (Canonical) | COC1=CC(=C(C(=C1C(=O)C=CC2=CC=CC=C2)O)OC)OC |
| SMILES (Isomeric) | COC1=CC(=C(C(=C1C(=O)C=CC2=CC=CC=C2)O)OC)OC |
| InChI | InChI=1S/C18H18O5/c1-21-14-11-15(22-2)18(23-3)17(20)16(14)13(19)10-9-12-7-5-4-6-8-12/h4-11,20H,1-3H3 |
| InChI Key | OCGIXADHTXAPKN-UHFFFAOYSA-N |
| Popularity | 3 references in papers |
| Molecular Formula | C18H18O5 |
| Molecular Weight | 314.30 g/mol |
| Exact Mass | 314.11542367 g/mol |
| Topological Polar Surface Area (TPSA) | 65.00 Ų |
| XlogP | 3.80 |
| There are no found synonyms. |
| Target | Value | Probability (raw) | Probability (%) |
|---|---|---|---|
| No predicted properties yet! | |||
Proven Targets:
| CHEMBL ID | UniProt ID | Name | Min activity | Assay type | Source |
|---|---|---|---|---|---|
| No proven targets yet! | |||||
Predicted Targets (via Super-PRED):
| CHEMBL ID | UniProt ID | Name | Probability | Model accuracy |
|---|---|---|---|---|
| CHEMBL5619 | P27695 | DNA-(apurinic or apyrimidinic site) lyase | 97.43% | 91.11% |
| CHEMBL1293249 | Q13887 | Kruppel-like factor 5 | 96.67% | 86.33% |
| CHEMBL3108638 | O15164 | Transcription intermediary factor 1-alpha | 95.49% | 95.56% |
| CHEMBL1075094 | Q16236 | Nuclear factor erythroid 2-related factor 2 | 94.70% | 96.00% |
| CHEMBL3251 | P19838 | Nuclear factor NF-kappa-B p105 subunit | 91.45% | 96.09% |
| CHEMBL3091268 | Q92753 | Nuclear receptor ROR-beta | 90.44% | 95.50% |
| CHEMBL3192 | Q9BY41 | Histone deacetylase 8 | 88.21% | 93.99% |
| CHEMBL3060 | Q9Y345 | Glycine transporter 2 | 87.68% | 99.17% |
| CHEMBL1821 | P08173 | Muscarinic acetylcholine receptor M4 | 84.54% | 94.08% |
| CHEMBL3194 | P02766 | Transthyretin | 84.23% | 90.71% |
| CHEMBL2535 | P11166 | Glucose transporter | 83.87% | 98.75% |
| CHEMBL2002 | P12268 | Inosine-5'-monophosphate dehydrogenase 2 | 83.86% | 98.21% |
| CHEMBL4208 | P20618 | Proteasome component C5 | 82.64% | 90.00% |
| CHEMBL1255126 | O15151 | Protein Mdm4 | 82.46% | 90.20% |
| CHEMBL1806 | P11388 | DNA topoisomerase II alpha | 80.81% | 89.00% |
| CHEMBL2716 | Q8WUI4 | Histone deacetylase 7 | 80.47% | 89.44% |
Below are displayed all the plants proven (via scientific papers) to contain this
compound!
To see more specific details click the taxa you are interested in.
To see more specific details click the taxa you are interested in.
| Monanthotaxis cauliflora |
| Piper dilatatum |
| Piper hispidum |
| Uvaria scheffleri |
| PubChem | 227450 |
| LOTUS | LTS0140795 |
| wikiData | Q105189344 |