9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione

Details

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Internal ID 41c5e51a-3f44-4847-b3af-f0aa57dbb27c
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name 9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
SMILES (Canonical) CC1C(C(CC(O1)OC2CC(CC3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5O)(C(=O)C)O)N)O
SMILES (Isomeric) CC1C(C(CC(O1)OC2CC(CC3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5O)(C(=O)C)O)N)O
InChI InChI=1S/C26H27NO9/c1-10-22(30)15(27)7-18(35-10)36-17-9-26(34,11(2)28)8-12-6-14-21(24(32)19(12)17)25(33)20-13(23(14)31)4-3-5-16(20)29/h3-6,10,15,17-18,22,29-30,32,34H,7-9,27H2,1-2H3
InChI Key IVTIJSPMQMJSEQ-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H27NO9
Molecular Weight 497.50 g/mol
Exact Mass 497.16858144 g/mol
Topological Polar Surface Area (TPSA) 177.00 Ų
XlogP 1.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.71% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 98.90% 91.49%
CHEMBL1806 P11388 DNA topoisomerase II alpha 98.73% 89.00%
CHEMBL2581 P07339 Cathepsin D 96.52% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.41% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.08% 95.56%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 95.66% 96.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.89% 97.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.42% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.07% 86.33%
CHEMBL226 P30542 Adenosine A1 receptor 91.99% 95.93%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.70% 95.89%
CHEMBL4208 P20618 Proteasome component C5 88.52% 90.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 88.44% 92.94%
CHEMBL340 P08684 Cytochrome P450 3A4 88.15% 91.19%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.07% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.81% 94.45%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 84.95% 99.15%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.80% 91.07%
CHEMBL2056 P21728 Dopamine D1 receptor 84.18% 91.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.86% 94.00%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 83.48% 83.10%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 81.74% 96.21%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.28% 93.03%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.04% 90.71%
CHEMBL4530 P00488 Coagulation factor XIII 80.67% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 85142297
LOTUS LTS0218200
wikiData Q104169178