(1R,4aS,4bS,7R,8S,8aS,10aS)-8-(6-hydroxy-1H-indol-3-yl)-1,4b,7,8,10a-pentamethyl-1,3,4,4a,5,6,7,8a,9,10-decahydrophenanthren-2-one

Details

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Internal ID e9a28b2d-1fc0-4825-97c5-1553a544216c
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Colensane and clerodane diterpenoids
IUPAC Name (1R,4aS,4bS,7R,8S,8aS,10aS)-8-(6-hydroxy-1H-indol-3-yl)-1,4b,7,8,10a-pentamethyl-1,3,4,4a,5,6,7,8a,9,10-decahydrophenanthren-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H37NO2/c1-16-10-12-26(4)23-9-8-22(30)17(2)25(23,3)13-11-24(26)27(16,5)20-15-28-21-14-18(29)6-7-19(20)21/h6-7,14-17,23-24,28-29H,8-13H2,1-5H3/t16-,17+,23-,24+,25-,26+,27-/m1/s1
InChI Key JZXJOUCZGSLUPN-PEZJXMIGSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C27H37NO2
Molecular Weight 407.60 g/mol
Exact Mass 407.282429423 g/mol
Topological Polar Surface Area (TPSA) 53.10 Ų
XlogP 7.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (1R,4aS,4bS,7R,8S,8aS,10aS)-8-(6-hydroxy-1H-indol-3-yl)-1,4b,7,8,10a-pentamethyl-1,3,4,4a,5,6,7,8a,9,10-decahydrophenanthren-2-one

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.60% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.80% 94.45%
CHEMBL1951 P21397 Monoamine oxidase A 95.74% 91.49%
CHEMBL1937 Q92769 Histone deacetylase 2 94.01% 94.75%
CHEMBL2581 P07339 Cathepsin D 93.78% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.35% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.05% 97.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 91.13% 92.94%
CHEMBL1994 P08235 Mineralocorticoid receptor 91.09% 100.00%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 89.85% 93.40%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.25% 89.00%
CHEMBL2535 P11166 Glucose transporter 87.53% 98.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.76% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 86.69% 93.99%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 84.73% 90.71%
CHEMBL217 P14416 Dopamine D2 receptor 84.67% 95.62%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.51% 82.69%
CHEMBL213 P08588 Beta-1 adrenergic receptor 82.06% 95.56%
CHEMBL4581 P52732 Kinesin-like protein 1 81.96% 93.18%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.88% 99.23%
CHEMBL3038469 P24941 CDK2/Cyclin A 80.92% 91.38%
CHEMBL242 Q92731 Estrogen receptor beta 80.09% 98.35%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 101616406
LOTUS LTS0010645
wikiData Q105137699