(-)-Placodiolic acid

Details

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Internal ID 0e4de344-8687-4db6-9069-dfc9ef76e16d
Taxonomy Benzenoids > Benzene and substituted derivatives > Acetophenones
IUPAC Name (4aS,9bS)-2,8-diacetyl-1,7,9-trihydroxy-4a-methoxy-6,9b-dimethyl-4H-dibenzofuran-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H20O8/c1-7-14(23)12(9(3)21)15(24)13-16(7)27-19(26-5)6-10(22)11(8(2)20)17(25)18(13,19)4/h23-25H,6H2,1-5H3/t18-,19-/m0/s1
InChI Key TUENYOIQMXRNRF-OALUTQOASA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C19H20O8
Molecular Weight 376.40 g/mol
Exact Mass 376.11581759 g/mol
Topological Polar Surface Area (TPSA) 130.00 Ų
XlogP 1.80

Synonyms

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RefChem:67934
(4aS,9bS)-2,8-diacetyl-1,7,9-trihydroxy-4a-methoxy-6,9b-dimethyl-4H-dibenzofuran-3-one
CHEBI:204323
(4aS,9bS)-2,8-diacetyl-1,7,9-trihydroxy-4a-methoxy-6,9b-dimethyl-4H-dibenzouran-3-one

2D Structure

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2D Structure of (-)-Placodiolic acid

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.24% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 97.24% 83.82%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 92.60% 85.30%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.69% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.69% 89.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.11% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.90% 94.45%
CHEMBL340 P08684 Cytochrome P450 3A4 85.36% 91.19%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.26% 94.00%
CHEMBL2581 P07339 Cathepsin D 85.24% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.11% 95.56%
CHEMBL3401 O75469 Pregnane X receptor 83.77% 94.73%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 82.72% 82.38%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 82.13% 93.65%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.56% 91.07%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.58% 86.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 101821330
LOTUS LTS0124682
wikiData Q77385149