(+)-Papaveroxinoline

Details

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Internal ID e7431ca1-c7b2-4bb9-92f9-c8ba3c37298d
Taxonomy Organoheterocyclic compounds > Isoquinolines and derivatives > Benzylisoquinolines
IUPAC Name [[2-(hydroxymethyl)-3,4-dimethoxyphenyl]-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl] acetate
SMILES (Canonical) CC(=O)OC(C1C2=C(C3=C(C=C2CCN1C)OCO3)OC)C4=C(C(=C(C=C4)OC)OC)CO
SMILES (Isomeric) CC(=O)OC(C1C2=C(C3=C(C=C2CCN1C)OCO3)OC)C4=C(C(=C(C=C4)OC)OC)CO
InChI InChI=1S/C24H29NO8/c1-13(27)33-22(15-6-7-17(28-3)21(29-4)16(15)11-26)20-19-14(8-9-25(20)2)10-18-23(24(19)30-5)32-12-31-18/h6-7,10,20,22,26H,8-9,11-12H2,1-5H3
InChI Key HHJKQBLXEZPDNY-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C24H29NO8
Molecular Weight 459.50 g/mol
Exact Mass 459.18931688 g/mol
Topological Polar Surface Area (TPSA) 95.90 Ų
XlogP 2.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of (+)-Papaveroxinoline

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.36% 96.09%
CHEMBL261 P00915 Carbonic anhydrase I 95.85% 96.76%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 95.80% 96.77%
CHEMBL2581 P07339 Cathepsin D 95.20% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.19% 94.45%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 93.43% 92.62%
CHEMBL2413 P32246 C-C chemokine receptor type 1 92.47% 89.50%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.01% 95.56%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.64% 95.89%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.12% 85.14%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.21% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.12% 86.33%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.87% 99.17%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 88.56% 89.62%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.01% 91.11%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.59% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.80% 89.00%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 85.12% 95.78%
CHEMBL5555 O00767 Acyl-CoA desaturase 84.70% 97.50%
CHEMBL340 P08684 Cytochrome P450 3A4 84.22% 91.19%
CHEMBL2535 P11166 Glucose transporter 83.67% 98.75%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 82.84% 100.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.46% 97.14%
CHEMBL4208 P20618 Proteasome component C5 81.16% 90.00%
CHEMBL4072 P07858 Cathepsin B 80.90% 93.67%
CHEMBL3192 Q9BY41 Histone deacetylase 8 80.51% 93.99%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Papaver orientale

Cross-Links

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PubChem 14106962
LOTUS LTS0083563
wikiData Q105028321