(-)-Longamide B

Details

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Internal ID 9e267136-061f-4867-a50c-edc9ac684b1f
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Carboxylic acid derivatives > Carboxylic acid amides > 2-heteroaryl carboxamides
IUPAC Name 2-[(4S)-6,7-dibromo-1-oxo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-4-yl]acetic acid
SMILES (Canonical) C1C(N2C(=CC(=C2Br)Br)C(=O)N1)CC(=O)O
SMILES (Isomeric) C1[C@@H](N2C(=CC(=C2Br)Br)C(=O)N1)CC(=O)O
InChI InChI=1S/C9H8Br2N2O3/c10-5-2-6-9(16)12-3-4(1-7(14)15)13(6)8(5)11/h2,4H,1,3H2,(H,12,16)(H,14,15)/t4-/m0/s1
InChI Key DRDCMECERMJRNR-BYPYZUCNSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C9H8Br2N2O3
Molecular Weight 351.98 g/mol
Exact Mass 351.88812 g/mol
Topological Polar Surface Area (TPSA) 71.30 Ų
XlogP 1.20

Synonyms

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(-)-Longamide B
CHEMBL465779
2-[(4S)-6,7-dibromo-1-oxo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-4-yl]acetic acid

2D Structure

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2D Structure of (-)-Longamide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.17% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.10% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.01% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.98% 85.14%
CHEMBL4208 P20618 Proteasome component C5 91.67% 90.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 91.53% 93.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.27% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.50% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.29% 94.45%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 81.59% 90.24%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 81.57% 89.62%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.63% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11602770
LOTUS LTS0211299
wikiData Q104987336