Details

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Internal ID 51ddcd44-4f5e-4e85-9650-a1d22f7c4cdf
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C76H114N20O22S/c1-38(2)30-48-64(104)85-50(33-56(78)100)66(106)91-59(41(6)98)73(113)94(11)35-57(101)118-42(7)60(74(114)95(12)53(68(108)86-48)26-27-55(77)99)92-67(107)52(36-119(115,116)117)89-63(103)47(24-18-28-81-75(79)80)84-65(105)49(32-44-34-82-46-23-17-16-22-45(44)46)87-70(110)58(39(3)4)90-71(111)61(76(8,9)10)93-69(109)54-25-19-29-96(54)72(112)51(31-43-20-14-13-15-21-43)88-62(102)40(5)83-37-97/h13-17,20-23,34,37-42,47-54,58-61,82,98H,18-19,24-33,35-36H2,1-12H3,(H2,77,99)(H2,78,100)(H,83,97)(H,84,105)(H,85,104)(H,86,108)(H,87,110)(H,88,102)(H,89,103)(H,90,111)(H,91,106)(H,92,107)(H,93,109)(H4,79,80,81)(H,115,116,117)
InChI Key UYSZNAJNNZZLOS-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C76H114N20O22S
Molecular Weight 1691.90 g/mol
Exact Mass 1690.81372652 g/mol
Topological Polar Surface Area (TPSA) 654.00 Ų
XlogP -1.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.97% 98.95%
CHEMBL333 P08253 Matrix metalloproteinase-2 99.88% 96.31%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 99.87% 98.33%
CHEMBL3837 P07711 Cathepsin L 99.84% 96.61%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 99.73% 97.64%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 99.22% 91.81%
CHEMBL4801 P29466 Caspase-1 99.20% 96.85%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 99.10% 95.56%
CHEMBL4588 P22894 Matrix metalloproteinase 8 98.63% 94.66%
CHEMBL5103 Q969S8 Histone deacetylase 10 98.47% 90.08%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 98.24% 88.42%
CHEMBL4123 P30989 Neurotensin receptor 1 98.23% 96.67%
CHEMBL3729 P22748 Carbonic anhydrase IV 97.95% 99.23%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.77% 91.11%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 97.35% 95.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 97.31% 85.31%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.28% 96.09%
CHEMBL2514 O95665 Neurotensin receptor 2 97.24% 100.00%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 96.99% 97.31%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 96.82% 96.67%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 96.50% 97.23%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 96.19% 96.47%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 95.89% 82.38%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 95.53% 96.90%
CHEMBL321 P14780 Matrix metalloproteinase 9 95.47% 92.12%
CHEMBL4227 P25090 Lipoxin A4 receptor 94.93% 100.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 94.89% 85.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.81% 97.09%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 94.70% 96.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.09% 99.23%
CHEMBL5028 O14672 ADAM10 93.02% 97.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 92.99% 97.14%
CHEMBL4625 Q07817 Apoptosis regulator Bcl-X 92.82% 99.77%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.73% 89.00%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 92.57% 98.24%
CHEMBL3310 Q96DB2 Histone deacetylase 11 92.48% 88.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 92.19% 93.00%
CHEMBL1914 P06276 Butyrylcholinesterase 92.16% 95.00%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 91.64% 96.11%
CHEMBL332 P03956 Matrix metalloproteinase-1 91.58% 94.50%
CHEMBL4644 P41968 Melanocortin receptor 3 91.44% 99.52%
CHEMBL259 P32245 Melanocortin receptor 4 91.27% 95.38%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 91.07% 95.17%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 90.90% 95.34%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.70% 93.56%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 90.21% 98.94%
CHEMBL2072 P35499 Sodium channel protein type IV alpha subunit 89.96% 92.32%
CHEMBL340 P08684 Cytochrome P450 3A4 89.67% 91.19%
CHEMBL230 P35354 Cyclooxygenase-2 89.54% 89.63%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 89.20% 100.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.08% 97.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.72% 95.89%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.64% 93.03%
CHEMBL4072 P07858 Cathepsin B 88.40% 93.67%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.11% 99.17%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 87.84% 95.52%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 87.82% 96.03%
CHEMBL4073 P09237 Matrix metalloproteinase 7 87.81% 97.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 86.76% 96.00%
CHEMBL2803 P43403 Tyrosine-protein kinase ZAP-70 86.24% 82.50%
CHEMBL1293287 P14735 Insulin-degrading enzyme 86.22% 88.10%
CHEMBL2730 P21980 Protein-glutamine gamma-glutamyltransferase 85.82% 92.38%
CHEMBL1937 Q92769 Histone deacetylase 2 85.45% 94.75%
CHEMBL4302 P08183 P-glycoprotein 1 85.42% 92.98%
CHEMBL2535 P11166 Glucose transporter 85.17% 98.75%
CHEMBL5646 Q6L5J4 FML2_HUMAN 84.86% 100.00%
CHEMBL2327 P21452 Neurokinin 2 receptor 84.50% 98.89%
CHEMBL2094135 Q96BI3 Gamma-secretase 84.32% 98.05%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 83.63% 90.93%
CHEMBL4393 P39900 Matrix metalloproteinase 12 83.57% 92.22%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 82.82% 100.00%
CHEMBL261 P00915 Carbonic anhydrase I 82.64% 96.76%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 82.51% 95.83%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.41% 85.14%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.40% 95.50%
CHEMBL3869 P50281 Matrix metalloproteinase 14 81.22% 93.10%
CHEMBL255 P29275 Adenosine A2b receptor 80.47% 98.59%
CHEMBL1795185 Q58F21 Bromodomain testis-specific protein 80.36% 89.76%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 16132385
LOTUS LTS0182378
wikiData Q104403094