(-)-6-epi-notoamide I

Details

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Internal ID 70695628-20bd-4833-a8ba-e7ddaf416cf6
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Pyrroloquinolines
IUPAC Name (1S,17S,19R)-9,9,16,16-tetramethyl-8-oxa-14,23,25-triazaheptacyclo[17.5.2.01,17.03,15.04,13.07,12.019,23]hexacosa-3(15),4(13),5,7(12),10-pentaene-2,24,26-trione
SMILES (Canonical) CC1(C=CC2=C(O1)C=CC3=C2NC4=C3C(=O)C56C(C4(C)C)CC7(CCCN7C5=O)C(=O)N6)C
SMILES (Isomeric) CC1(C=CC2=C(O1)C=CC3=C2NC4=C3C(=O)[C@@]56[C@H](C4(C)C)C[C@]7(CCCN7C5=O)C(=O)N6)C
InChI InChI=1S/C26H27N3O4/c1-23(2)10-8-13-15(33-23)7-6-14-17-19(27-18(13)14)24(3,4)16-12-25-9-5-11-29(25)22(32)26(16,20(17)30)28-21(25)31/h6-8,10,16,27H,5,9,11-12H2,1-4H3,(H,28,31)/t16-,25+,26-/m0/s1
InChI Key CDJZXTFDGOKTOT-HKFLSJHISA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H27N3O4
Molecular Weight 445.50 g/mol
Exact Mass 445.20015635 g/mol
Topological Polar Surface Area (TPSA) 91.50 Ų
XlogP 3.10

Synonyms

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(1S,17S,19R)-9,9,16,16-tetramethyl-8-oxa-14,23,25-triazaheptacyclo[17.5.2.01,17.03,15.04,13.07,12.019,23]hexacosa-3(15),4(13),5,7(12),10-pentaene-2,24,26-trione
(1S,17S,19R)-9,9,16,16-tetramethyl-8-oxa-14,23,25-triazaheptacyclo(17.5.2.01,17.03,15.04,13.07,12.019,23)hexacosa-3(15),4(13),5,7(12),10-pentaene-2,24,26-trione
RefChem:67667
CHEBI:217613

2D Structure

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2D Structure of (-)-6-epi-notoamide I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.06% 94.45%
CHEMBL2581 P07339 Cathepsin D 98.09% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 97.21% 93.40%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 96.61% 96.77%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.93% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.72% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.61% 91.11%
CHEMBL1937 Q92769 Histone deacetylase 2 92.09% 94.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.08% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.96% 97.25%
CHEMBL3192 Q9BY41 Histone deacetylase 8 91.10% 93.99%
CHEMBL255 P29275 Adenosine A2b receptor 90.63% 98.59%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.13% 95.56%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 89.56% 93.04%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.43% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.71% 89.00%
CHEMBL4208 P20618 Proteasome component C5 87.68% 90.00%
CHEMBL3310 Q96DB2 Histone deacetylase 11 87.00% 88.56%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 84.07% 94.80%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.05% 100.00%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 83.98% 80.96%
CHEMBL2916 O14746 Telomerase reverse transcriptase 83.41% 90.00%
CHEMBL4829 O00763 Acetyl-CoA carboxylase 2 83.17% 98.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.63% 95.89%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 82.46% 96.67%
CHEMBL3012 Q13946 Phosphodiesterase 7A 80.70% 99.29%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 132487496
LOTUS LTS0097880
wikiData Q104954530