tunicamycin A

Details

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Internal ID ae458eaf-7030-4062-8ff2-b6de1c39259d
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbohydrates and carbohydrate conjugates > Aminosaccharides > N-acyl-alpha-hexosamines
IUPAC Name (E)-N-[(2S,3R,4R,5R,6R)-2-[(2S,3S,4S,5R,6S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl]-4,5-dihydroxyoxan-3-yl]-13-methyltetradec-2-enamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C38H62N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h12,14-16,19,21-23,26-37,43,45,48-53H,4-11,13,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/b14-12+/t21-,22-,23+,26+,27-,28+,29+,30+,31-,32+,33-,34-,35-,36+,37+/m1/s1
InChI Key MEYZYGMYMLNUHJ-HFMVIZMTSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C38H62N4O16
Molecular Weight 830.90 g/mol
Exact Mass 830.41608190 g/mol
Topological Polar Surface Area (TPSA) 306.00 Ų
XlogP 0.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of tunicamycin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.08% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.42% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.28% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.95% 91.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 96.18% 99.17%
CHEMBL3401 O75469 Pregnane X receptor 93.73% 94.73%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.08% 89.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.24% 93.56%
CHEMBL2123 P51582 Pyrimidinergic receptor P2Y4 89.29% 93.39%
CHEMBL1937 Q92769 Histone deacetylase 2 88.26% 94.75%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 88.03% 95.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 87.37% 95.89%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 86.56% 96.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.40% 90.71%
CHEMBL4588 P22894 Matrix metalloproteinase 8 85.11% 94.66%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 84.91% 95.83%
CHEMBL255 P29275 Adenosine A2b receptor 84.56% 98.59%
CHEMBL5103 Q969S8 Histone deacetylase 10 84.24% 90.08%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.89% 94.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 82.55% 95.56%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 81.01% 89.67%
CHEMBL5255 O00206 Toll-like receptor 4 80.64% 92.50%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.48% 85.14%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 80.39% 86.92%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 80.34% 89.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 145720586
LOTUS LTS0229588
wikiData Q105162479