Sporidesmin B

Details

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Internal ID be93eae3-ac2e-40b4-8f3f-6df5598b5456
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyrroloindoles
IUPAC Name 6-chloro-3-hydroxy-7,8-dimethoxy-10,14,18-trimethyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-triene-13,17-dione
SMILES (Canonical) CC12C(=O)N3C4C(CC3(C(=O)N1C)SS2)(C5=CC(=C(C(=C5N4C)OC)OC)Cl)O
SMILES (Isomeric) CC12C(=O)N3C4C(CC3(C(=O)N1C)SS2)(C5=CC(=C(C(=C5N4C)OC)OC)Cl)O
InChI InChI=1S/C18H20ClN3O5S2/c1-16-14(23)22-13-17(25,7-18(22,29-28-16)15(24)21(16)3)8-6-9(19)11(26-4)12(27-5)10(8)20(13)2/h6,13,25H,7H2,1-5H3
InChI Key HCAHETRFJITQNU-UHFFFAOYSA-N
Popularity 42 references in papers

Physical and Chemical Properties

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Molecular Formula C18H20ClN3O5S2
Molecular Weight 458.00 g/mol
Exact Mass 457.0532908 g/mol
Topological Polar Surface Area (TPSA) 133.00 Ų
XlogP 1.20

Synonyms

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3351-96-0
0YY87TLX8U
NSC-246153
6-chloro-3-hydroxy-7,8-dimethoxy-10,14,18-trimethyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-triene-13,17-dione
3,11a-Epidithio-11aH-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-dione, 9-chloro-2,3,5a,6,10b,11-hexahydro-10b-hydroxy-7,8-dimethoxy-2,3,6-trimethyl-
6-chloro-3-hydroxy-7,8-dimethoxy-10,14,18-trimethyl-15,16-dithia-10,12,18-triazapentacyclo(12.2.2.01,12.03,11.04,9)octadeca-4,6,8-triene-13,17-dione
RefChem:185020
UNII-0YY87TLX8U
NSC 246153
SPORIDESMINE B
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Sporidesmin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 96.83% 96.77%
CHEMBL4040 P28482 MAP kinase ERK2 95.98% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.43% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.42% 98.95%
CHEMBL4208 P20618 Proteasome component C5 92.14% 90.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.76% 86.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.07% 91.11%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.42% 94.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.84% 95.56%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 86.90% 93.40%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.24% 94.45%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 85.06% 96.95%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.58% 93.99%
CHEMBL217 P14416 Dopamine D2 receptor 80.92% 95.62%
CHEMBL340 P08684 Cytochrome P450 3A4 80.76% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 99878
LOTUS LTS0181634
wikiData Q27237363