Punaglandin 8

Details

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Internal ID a4e6e1fb-2b59-4f77-a1b3-fff88fdb44ab
Taxonomy Lipids and lipid-like molecules > Fatty Acyls > Eicosanoids > Clavulones and derivatives
IUPAC Name methyl (Z,7S)-7-acetyloxy-7-[(1R,2S)-4-chloro-2-hydroxy-2-[(Z)-oct-2-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H33ClO6/c1-4-5-6-7-8-12-15-23(28)16-18(24)22(27)21(23)19(30-17(2)25)13-10-9-11-14-20(26)29-3/h8,10,12-13,16,19,21,28H,4-7,9,11,14-15H2,1-3H3/b12-8-,13-10-/t19-,21-,23+/m0/s1
InChI Key LAWSLZINBLIPFW-WAALSUGPSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C23H33ClO6
Molecular Weight 441.00 g/mol
Exact Mass 440.1965665 g/mol
Topological Polar Surface Area (TPSA) 89.90 Ų
XlogP 4.40

Synonyms

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methyl 7S-acetoxy-9-oxo-10-chloro-12S-hydroxy-5Z,10E,14Z-prostatrienoate-cyclo[8R,12S]
LMFA03120045
CHEBI:169489
methyl (Z,7S)-7-acetyloxy-7-[(1R,2S)-4-chloro-2-hydroxy-2-[(Z)-oct-2-enyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoate

2D Structure

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2D Structure of Punaglandin 8

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.68% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.61% 94.45%
CHEMBL2581 P07339 Cathepsin D 97.08% 98.95%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.49% 99.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.38% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.36% 97.25%
CHEMBL221 P23219 Cyclooxygenase-1 94.23% 90.17%
CHEMBL299 P17252 Protein kinase C alpha 91.32% 98.03%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 90.64% 89.34%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.26% 93.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 88.24% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 86.26% 94.73%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 86.00% 96.00%
CHEMBL340 P08684 Cytochrome P450 3A4 84.23% 91.19%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.06% 96.90%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 83.97% 92.86%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 83.47% 97.21%
CHEMBL5255 O00206 Toll-like receptor 4 83.34% 92.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.81% 86.33%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.48% 95.50%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.87% 94.33%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.71% 92.88%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 80.68% 97.29%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 5283260
LOTUS LTS0066250
wikiData Q76293874