Madindoline A

Details

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Internal ID 250cb036-3e74-4cac-af3a-319bd3ad5747
Taxonomy Organoheterocyclic compounds > Indoles and derivatives
IUPAC Name 2-[(8b-hydroxy-2,3a-dihydro-1H-furo[2,3-b]indol-4-yl)methyl]-4-butyl-2,5-dimethylcyclopent-4-ene-1,3-dione
SMILES (Canonical) CCCCC1=C(C(=O)C(C1=O)(C)CN2C3C(CCO3)(C4=CC=CC=C42)O)C
SMILES (Isomeric) CCCCC1=C(C(=O)C(C1=O)(C)CN2C3C(CCO3)(C4=CC=CC=C42)O)C
InChI InChI=1S/C22H27NO4/c1-4-5-8-15-14(2)18(24)21(3,19(15)25)13-23-17-10-7-6-9-16(17)22(26)11-12-27-20(22)23/h6-7,9-10,20,26H,4-5,8,11-13H2,1-3H3
InChI Key XPVQXXLKOCZMGG-UHFFFAOYSA-N
Popularity 11 references in papers

Physical and Chemical Properties

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Molecular Formula C22H27NO4
Molecular Weight 369.50 g/mol
Exact Mass 369.19400834 g/mol
Topological Polar Surface Area (TPSA) 66.80 Ų
XlogP 3.30

Synonyms

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184877-64-3

2D Structure

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2D Structure of Madindoline A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.85% 98.95%
CHEMBL240 Q12809 HERG 96.63% 89.76%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.43% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.70% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.06% 95.56%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.94% 82.69%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.01% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.08% 97.25%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.69% 97.09%
CHEMBL230 P35354 Cyclooxygenase-2 85.52% 89.63%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.78% 99.23%
CHEMBL5805 Q9NR97 Toll-like receptor 8 82.28% 96.25%
CHEMBL5028 O14672 ADAM10 81.21% 97.50%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 80.96% 85.94%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.16% 89.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.14% 82.38%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 9799462
LOTUS LTS0091134
wikiData Q104201228