Laccarin A

Details

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Internal ID 12e0f210-bb9a-41fb-9dd4-24bf58729ae2
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Amino acids and derivatives > Gamma amino acids and derivatives
IUPAC Name (7S,7aR)-3-acetyl-4-(4-aminobutanoyl)-7-methyl-5,6,7,7a-tetrahydro-1H-pyrrolo[3,2-b]pyridin-2-one
SMILES (Canonical) CC1CCN(C2=C(C(=O)NC12)C(=O)C)C(=O)CCCN
SMILES (Isomeric) C[C@H]1CCN(C2=C(C(=O)N[C@H]12)C(=O)C)C(=O)CCCN
InChI InChI=1S/C14H21N3O3/c1-8-5-7-17(10(19)4-3-6-15)13-11(9(2)18)14(20)16-12(8)13/h8,12H,3-7,15H2,1-2H3,(H,16,20)/t8-,12+/m0/s1
InChI Key VXFFZKQBHIIPCJ-QPUJVOFHSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C14H21N3O3
Molecular Weight 279.33 g/mol
Exact Mass 279.15829154 g/mol
Topological Polar Surface Area (TPSA) 92.50 Ų
XlogP -1.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Laccarin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.22% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.40% 97.25%
CHEMBL2581 P07339 Cathepsin D 97.02% 98.95%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.80% 97.09%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 92.01% 82.69%
CHEMBL4581 P52732 Kinesin-like protein 1 89.66% 93.18%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 88.72% 93.04%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.04% 91.11%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.28% 93.03%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.50% 90.71%
CHEMBL3384 Q16512 Protein kinase N1 83.57% 80.71%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.37% 100.00%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 82.03% 94.33%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 81.99% 95.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 81.78% 93.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 81.38% 98.33%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.14% 100.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.25% 92.94%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.04% 94.45%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583283
LOTUS LTS0212325
wikiData Q75058519