Kojistatin A

Details

Top
Internal ID f4cd097f-dfbb-44aa-b5c3-8d89fddcd37b
Taxonomy Organoheterocyclic compounds > Epoxides > Oxirane carboxylic acids and derivatives > Oxirane carboxylic acids
IUPAC Name 3-[[1-[4-(3-aminopropylamino)butylamino]-3-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C17H32N4O5/c1-3-11(2)12(21-16(23)13-14(26-13)17(24)25)15(22)20-10-5-4-8-19-9-6-7-18/h11-14,19H,3-10,18H2,1-2H3,(H,20,22)(H,21,23)(H,24,25)
InChI Key HUAJESHKPMHHPE-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C17H32N4O5
Molecular Weight 372.50 g/mol
Exact Mass 372.23727013 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP -2.60

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Kojistatin A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.29% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.96% 96.09%
CHEMBL2514 O95665 Neurotensin receptor 2 93.62% 100.00%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 92.18% 97.29%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.90% 99.17%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 91.19% 95.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 90.49% 100.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.18% 91.11%
CHEMBL3492 P49721 Proteasome Macropain subunit 88.17% 90.24%
CHEMBL340 P08684 Cytochrome P450 3A4 87.98% 91.19%
CHEMBL2413 P32246 C-C chemokine receptor type 1 87.07% 89.50%
CHEMBL3401 O75469 Pregnane X receptor 86.99% 94.73%
CHEMBL3776 Q14790 Caspase-8 86.82% 97.06%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.31% 98.33%
CHEMBL5028 O14672 ADAM10 84.94% 97.50%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 84.83% 97.23%
CHEMBL4581 P52732 Kinesin-like protein 1 84.77% 93.18%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 84.56% 96.47%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.96% 90.71%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.87% 95.56%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 83.76% 97.21%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.67% 93.56%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 83.22% 100.00%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 83.19% 96.00%
CHEMBL3308 P55212 Caspase-6 81.90% 97.56%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.65% 94.33%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 81.13% 96.95%
CHEMBL2094135 Q96BI3 Gamma-secretase 80.17% 98.05%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 85153105
LOTUS LTS0149256
wikiData Q77505832