Formicamycin D

Details

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Internal ID 27c349be-9bc1-4f29-a4d8-c9a1a218f586
Taxonomy Benzenoids > Benzene and substituted derivatives > Biphenyls and derivatives > Chlorinated biphenyls > Polychlorinated biphenyls
IUPAC Name (5aR,11aR)-1,10-dichloro-7-(3-chloro-6-hydroxy-4-methoxy-2-methylphenyl)-2,4,5a-trihydroxy-9-methoxy-12,12-dimethyl-11,11a-dihydrotetracene-5,6-dione
SMILES (Canonical) CC1=C(C(=CC(=C1Cl)OC)O)C2=CC(=C(C3=C2C(=O)C4(C(C3)C(C5=C(C4=O)C(=CC(=C5Cl)O)O)(C)C)O)Cl)OC
SMILES (Isomeric) CC1=C(C(=CC(=C1Cl)OC)O)C2=CC(=C(C3=C2C(=O)[C@@]4([C@H](C3)C(C5=C(C4=O)C(=CC(=C5Cl)O)O)(C)C)O)Cl)OC
InChI InChI=1S/C29H25Cl3O8/c1-10-19(14(34)9-17(40-5)23(10)30)11-6-16(39-4)24(31)12-7-18-28(2,3)22-21(13(33)8-15(35)25(22)32)27(37)29(18,38)26(36)20(11)12/h6,8-9,18,33-35,38H,7H2,1-5H3/t18-,29-/m1/s1
InChI Key RRDKRMMBMWKANR-LDLUVENISA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C29H25Cl3O8
Molecular Weight 607.90 g/mol
Exact Mass 606.061501 g/mol
Topological Polar Surface Area (TPSA) 134.00 Ų
XlogP 7.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Formicamycin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.02% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.89% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.32% 86.33%
CHEMBL1937 Q92769 Histone deacetylase 2 93.17% 94.75%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 92.15% 96.00%
CHEMBL2581 P07339 Cathepsin D 91.76% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.68% 94.45%
CHEMBL2535 P11166 Glucose transporter 90.57% 98.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.99% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.68% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 89.29% 93.99%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.95% 95.89%
CHEMBL2056 P21728 Dopamine D1 receptor 87.72% 91.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 87.23% 96.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.35% 94.00%
CHEMBL4040 P28482 MAP kinase ERK2 85.57% 83.82%
CHEMBL241 Q14432 Phosphodiesterase 3A 84.86% 92.94%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 84.79% 99.15%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.56% 97.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.15% 96.77%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.06% 89.00%
CHEMBL2337 P48067 Glycine transporter 1 82.55% 95.45%
CHEMBL217 P14416 Dopamine D2 receptor 81.23% 95.62%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.92% 93.03%
CHEMBL4805 Q99572 P2X purinoceptor 7 80.72% 97.50%
CHEMBL3194 P02766 Transthyretin 80.24% 90.71%
CHEMBL4208 P20618 Proteasome component C5 80.16% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684584
LOTUS LTS0046157
wikiData Q105243965