Euphorbialoid F

Details

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Internal ID 9fd1ae31-56e0-4f8a-a0e1-241b0e50e919
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Pentacarboxylic acids and derivatives
IUPAC Name [(1S,2R,3R,4S,5S,7R,8S,9R,10R,11S)-2,7-diacetyloxy-11-(2-acetyloxypropan-2-yl)-5,9-dimethyl-14-oxo-4-propanoyloxy-16-oxatetracyclo[7.5.2.01,10.03,7]hexadec-12-en-8-yl] pyridine-3-carboxylate
SMILES (Canonical) CCC(=O)OC1C(CC2(C1C(C34COC(C3C(C=CC4=O)C(C)(C)OC(=O)C)(C2OC(=O)C5=CN=CC=C5)C)OC(=O)C)OC(=O)C)C
SMILES (Isomeric) CCC(=O)O[C@H]1[C@H](C[C@]2([C@H]1[C@H]([C@@]34CO[C@]([C@@H]3[C@H](C=CC4=O)C(C)(C)OC(=O)C)([C@@H]2OC(=O)C5=CN=CC=C5)C)OC(=O)C)OC(=O)C)C
InChI InChI=1S/C35H43NO12/c1-9-25(41)45-27-18(2)15-35(48-21(5)39)26(27)29(44-19(3)37)34-17-43-33(8,31(35)46-30(42)22-11-10-14-36-16-22)28(34)23(12-13-24(34)40)32(6,7)47-20(4)38/h10-14,16,18,23,26-29,31H,9,15,17H2,1-8H3/t18-,23-,26+,27-,28-,29+,31-,33+,34+,35+/m0/s1
InChI Key PCIUYMZKLOLSFK-ZAJKPFSGSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C35H43NO12
Molecular Weight 669.70 g/mol
Exact Mass 669.27852581 g/mol
Topological Polar Surface Area (TPSA) 171.00 Ų
XlogP 2.50

Synonyms

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CHEMBL2030584

2D Structure

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2D Structure of Euphorbialoid F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 99.64% 89.34%
CHEMBL2581 P07339 Cathepsin D 98.94% 98.95%
CHEMBL2996 Q05655 Protein kinase C delta 98.58% 97.79%
CHEMBL1293249 Q13887 Kruppel-like factor 5 97.00% 86.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.76% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.88% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.60% 97.25%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 95.35% 81.11%
CHEMBL1293294 P51151 Ras-related protein Rab-9A 91.79% 87.67%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.97% 99.23%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.69% 91.07%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.17% 89.00%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 86.20% 91.24%
CHEMBL3524 P56524 Histone deacetylase 4 84.64% 92.97%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 84.29% 98.75%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.28% 96.77%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.85% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.60% 100.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.35% 94.00%
CHEMBL4662 P28074 Proteasome Macropain subunit MB1 81.88% 93.85%
CHEMBL1902 P62942 FK506-binding protein 1A 81.28% 97.05%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 80.85% 95.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.78% 97.09%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 80.67% 96.90%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Euphorbia prolifera

Cross-Links

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PubChem 60168077
LOTUS LTS0096959
wikiData Q105205762