Divergolide T

Details

Top
Internal ID bf6b3b85-6edf-4c1a-a056-e39785b067fe
Taxonomy Phenylpropanoids and polyketides > Macrolactams
IUPAC Name (9R,10E,13S,16Z,18R,25R)-9-ethyl-4,25-dihydroxy-3,16-dimethyl-13-(2-methylpropyl)-14-oxa-20-azatetracyclo[16.6.1.05,24.021,25]pentacosa-1(24),2,4,10,16,21-hexaene-6,15,19,23-tetrone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H37NO7/c1-6-19-8-7-9-20(12-16(2)3)39-30(37)18(5)14-22-29(36)32-25-15-24(34)26-21(31(22,25)38)13-17(4)28(35)27(26)23(33)11-10-19/h7-8,13-16,19-20,22,35,38H,6,9-12H2,1-5H3,(H,32,36)/b8-7+,18-14-/t19-,20+,22-,31-/m0/s1
InChI Key XVZBBQXWAQFOEC-DOZSOBCQSA-N
Popularity 3 references in papers

Physical and Chemical Properties

Top
Molecular Formula C31H37NO7
Molecular Weight 535.60 g/mol
Exact Mass 535.25700252 g/mol
Topological Polar Surface Area (TPSA) 130.00 Ų
XlogP 4.20

Synonyms

Top
CHEMBL5203349

2D Structure

Top
2D Structure of Divergolide T

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.28% 91.11%
CHEMBL2581 P07339 Cathepsin D 98.17% 98.95%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 92.42% 85.11%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 92.30% 96.47%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 91.89% 93.40%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.32% 95.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 90.17% 93.99%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.03% 97.09%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 88.95% 96.21%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.30% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.14% 99.23%
CHEMBL4530 P00488 Coagulation factor XIII 87.91% 96.00%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.20% 93.56%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.84% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.80% 95.89%
CHEMBL4581 P52732 Kinesin-like protein 1 85.71% 93.18%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 85.69% 99.15%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 85.68% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.55% 97.25%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 85.32% 96.38%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.13% 90.71%
CHEMBL1937 Q92769 Histone deacetylase 2 84.77% 94.75%
CHEMBL4208 P20618 Proteasome component C5 83.53% 90.00%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 83.31% 90.93%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.87% 94.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.80% 93.03%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 82.34% 95.89%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.60% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.92% 86.33%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 80.54% 92.62%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 80.11% 93.04%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 146682913
LOTUS LTS0055632
wikiData Q105343273