Chaetomadrasin A

Details

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Internal ID 5ade9fb2-6c38-4a27-85a0-f95dec4185f6
Taxonomy Organoheterocyclic compounds > Isoindoles and derivatives > Isoindolines > Isoindolones
IUPAC Name (1R,9S,13R,15S,16S,17R,18S)-18-(1H-indol-3-ylmethyl)-7,9,15,16-tetramethyl-19-azatricyclo[11.7.0.01,17]icosa-7,11-diene-2,5,6,14,20-pentone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H36N2O5/c1-17-8-7-10-23-30(38)20(4)19(3)28-25(15-21-16-33-24-11-6-5-9-22(21)24)34-31(39)32(23,28)27(36)13-12-26(35)29(37)18(2)14-17/h5-7,9-11,14,16-17,19-20,23,25,28,33H,8,12-13,15H2,1-4H3,(H,34,39)/t17-,19+,20-,23-,25-,28-,32+/m0/s1
InChI Key ZVGDMFNGQGPHGS-BLKGCJBVSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C32H36N2O5
Molecular Weight 528.60 g/mol
Exact Mass 528.26242225 g/mol
Topological Polar Surface Area (TPSA) 113.00 Ų
XlogP 4.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Chaetomadrasin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1937 Q92769 Histone deacetylase 2 98.59% 94.75%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.56% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 98.50% 95.56%
CHEMBL2581 P07339 Cathepsin D 96.41% 98.95%
CHEMBL3310 Q96DB2 Histone deacetylase 11 93.86% 88.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.59% 99.23%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.59% 93.99%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 91.70% 97.64%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.93% 94.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.49% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.56% 92.62%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 88.01% 96.39%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.65% 90.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.55% 96.09%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 85.67% 90.71%
CHEMBL2996 Q05655 Protein kinase C delta 85.57% 97.79%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.49% 89.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.48% 100.00%
CHEMBL255 P29275 Adenosine A2b receptor 82.54% 98.59%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.45% 93.03%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.70% 85.14%
CHEMBL5805 Q9NR97 Toll-like receptor 8 81.22% 96.25%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 81.18% 89.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682644
LOTUS LTS0076679
wikiData Q105384269