Aghardipeptin B

Details

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Internal ID b92c8cb2-9e3b-4d11-b8b1-583cb52b25db
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name 6,18,24-tris(1H-indol-3-ylmethyl)-3-methyl-15-(2-methylpropyl)-21-propan-2-yl-1,4,7,13,16,19,22,25-octazatricyclo[25.3.0.09,13]triacontane-2,5,8,14,17,20,23,26-octone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C57H69N11O8/c1-31(2)24-46-57(76)68-23-13-21-48(68)54(73)62-43(25-34-28-58-40-17-9-6-14-37(34)40)50(69)61-33(5)56(75)67-22-12-20-47(67)53(72)63-45(27-36-30-60-42-19-11-8-16-39(36)42)52(71)66-49(32(3)4)55(74)64-44(51(70)65-46)26-35-29-59-41-18-10-7-15-38(35)41/h6-11,14-19,28-33,43-49,58-60H,12-13,20-27H2,1-5H3,(H,61,69)(H,62,73)(H,63,72)(H,64,74)(H,65,70)(H,66,71)
InChI Key GFHJBYMOXXILNJ-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C57H69N11O8
Molecular Weight 1036.20 g/mol
Exact Mass 1035.53305820 g/mol
Topological Polar Surface Area (TPSA) 263.00 Ų
XlogP 6.00

Synonyms

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DTXSID301334877

2D Structure

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2D Structure of Aghardipeptin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.73% 98.95%
CHEMBL333 P08253 Matrix metalloproteinase-2 99.24% 96.31%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.35% 91.11%
CHEMBL5103 Q969S8 Histone deacetylase 10 97.57% 90.08%
CHEMBL3524 P56524 Histone deacetylase 4 97.01% 92.97%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.01% 85.14%
CHEMBL1937 Q92769 Histone deacetylase 2 96.52% 94.75%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.47% 95.56%
CHEMBL3310 Q96DB2 Histone deacetylase 11 96.02% 88.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.85% 96.09%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 95.37% 90.71%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.43% 97.64%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.99% 97.09%
CHEMBL1949 P62937 Cyclophilin A 93.04% 98.57%
CHEMBL321 P14780 Matrix metalloproteinase 9 92.93% 92.12%
CHEMBL228 P31645 Serotonin transporter 92.15% 95.51%
CHEMBL253 P34972 Cannabinoid CB2 receptor 91.15% 97.25%
CHEMBL1902 P62942 FK506-binding protein 1A 89.64% 97.05%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.88% 95.89%
CHEMBL5203 P33316 dUTP pyrophosphatase 87.13% 99.18%
CHEMBL213 P08588 Beta-1 adrenergic receptor 86.88% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.65% 89.00%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 86.57% 91.43%
CHEMBL1978 P11511 Cytochrome P450 19A1 85.97% 91.76%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 83.37% 95.71%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.31% 93.03%
CHEMBL4040 P28482 MAP kinase ERK2 83.20% 83.82%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.98% 99.23%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 82.80% 83.10%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 81.98% 89.62%
CHEMBL2996 Q05655 Protein kinase C delta 81.68% 97.79%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.31% 82.38%
CHEMBL1951 P21397 Monoamine oxidase A 80.87% 91.49%
CHEMBL255 P29275 Adenosine A2b receptor 80.66% 98.59%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 80.66% 95.83%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 73798207
LOTUS LTS0081894
wikiData Q104167113