8-Epi-Malyngamide C

Details

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Internal ID 9b660e0d-be5e-45e3-91fa-43206252913a
Taxonomy Organoheterocyclic compounds > Oxepanes
IUPAC Name (E,7S)-N-[(Z)-3-chloro-2-[(1S,5R,6S)-5-hydroxy-2-oxo-7-oxabicyclo[4.1.0]heptan-1-yl]prop-2-enyl]-7-methoxytetradec-4-enamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H38ClNO5/c1-3-4-5-6-8-11-19(30-2)12-9-7-10-13-22(29)26-17-18(16-25)24-21(28)15-14-20(27)23(24)31-24/h7,9,16,19-20,23,27H,3-6,8,10-15,17H2,1-2H3,(H,26,29)/b9-7+,18-16-/t19-,20+,23-,24+/m0/s1
InChI Key WXDBUBIFYCCNLE-FTWIAXFRSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C24H38ClNO5
Molecular Weight 456.00 g/mol
Exact Mass 455.2438510 g/mol
Topological Polar Surface Area (TPSA) 88.20 Ų
XlogP 4.00

Synonyms

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DTXSID401236365
(E,7S)-N-((Z)-3-chloro-2-((1S,5R,6S)-5-hydroxy-2-oxo-7-oxabicyclo(4.1.0)heptan-1-yl)prop-2-enyl)-7-methoxytetradec-4-enamide
(E,7S)-N-[(Z)-3-chloro-2-[(1S,5R,6S)-5-hydroxy-2-oxo-7-oxabicyclo[4.1.0]heptan-1-yl]prop-2-enyl]-7-methoxytetradec-4-enamide
RefChem:107076
DTXCID101667537
(E,7S)-N-((Z)-3-chloro-2-((1S,2R,6S)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)heptan-6-yl)prop-2-enyl)-7-methoxytetradec-4-enamide
CHEMBL1079695
CHEBI:198223
(4E,7S)-N-{(2Z)-3-Chloro-2-[(1S,5R,6S)-5-hydroxy-2-oxo-7-oxabicyclo[4.1.0]heptan-1-yl]prop-2-en-1-yl}-7-methoxytetradec-4-enamide

2D Structure

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2D Structure of 8-Epi-Malyngamide C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL230 P35354 Cyclooxygenase-2 99.51% 89.63%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.20% 99.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.01% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.38% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.68% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.75% 96.09%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 94.74% 95.71%
CHEMBL299 P17252 Protein kinase C alpha 93.43% 98.03%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 92.95% 92.88%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 91.89% 97.29%
CHEMBL4588 P22894 Matrix metalloproteinase 8 91.76% 94.66%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 91.71% 96.00%
CHEMBL5255 O00206 Toll-like receptor 4 90.63% 92.50%
CHEMBL2664 P23526 Adenosylhomocysteinase 90.44% 86.67%
CHEMBL2996 Q05655 Protein kinase C delta 90.10% 97.79%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.74% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 89.56% 90.71%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.57% 99.23%
CHEMBL218 P21554 Cannabinoid CB1 receptor 88.39% 96.61%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.54% 93.56%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 86.29% 96.25%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 85.09% 95.50%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 84.61% 95.36%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 84.60% 91.81%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.73% 92.62%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 83.62% 96.67%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.45% 100.00%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 83.40% 90.24%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.12% 95.56%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 83.04% 92.86%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 82.59% 89.33%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.65% 96.90%
CHEMBL340 P08684 Cytochrome P450 3A4 81.57% 91.19%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.92% 97.50%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 80.21% 85.30%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.11% 90.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 45379966
LOTUS LTS0131193
wikiData Q75058913