8-Chlororugulovasine A

Details

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Internal ID 8c2e7dee-149a-4595-869a-e11d98aee6b4
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles > 3-alkylindoles
IUPAC Name (4S,5R)-8-chloro-3'-methyl-4-(methylamino)spiro[3,4-dihydro-1H-benzo[cd]indole-5,5'-furan]-2'-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H15ClN2O2/c1-8-6-16(21-15(8)20)10-3-4-11(17)14-13(10)9(7-19-14)5-12(16)18-2/h3-4,6-7,12,18-19H,5H2,1-2H3/t12-,16+/m0/s1
InChI Key SDYOUVJWVNBXPX-BLLLJJGKSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C16H15ClN2O2
Molecular Weight 302.75 g/mol
Exact Mass 302.0822054 g/mol
Topological Polar Surface Area (TPSA) 54.10 Ų
XlogP 2.50

Synonyms

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Toxin B (Penicillium islandicum)
59787-45-0
L5FM3F581N
DTXSID50208519
(4S,5R)-8-chloro-3'-methyl-4-(methylamino)spiro[3,4-dihydro-1H-benzo[cd]indole-5,5'-furan]-2'-one
(4S,5R)-8-chloro-3'-methyl-4-(methylamino)spiro(3,4-dihydro-1H-benzo(cd)indole-5,5'-furan)-2'-one
RefChem:107029
DTXCID50131010
UNII-L5FM3F581N
CHEBI:222552
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of 8-Chlororugulovasine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.90% 91.11%
CHEMBL4040 P28482 MAP kinase ERK2 97.28% 83.82%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.58% 95.56%
CHEMBL3192 Q9BY41 Histone deacetylase 8 94.32% 93.99%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 92.35% 94.80%
CHEMBL3401 O75469 Pregnane X receptor 91.55% 94.73%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 90.09% 93.03%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.06% 94.45%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 89.65% 85.11%
CHEMBL4208 P20618 Proteasome component C5 89.56% 90.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.28% 94.00%
CHEMBL2581 P07339 Cathepsin D 89.18% 98.95%
CHEMBL2996 Q05655 Protein kinase C delta 88.88% 97.79%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 88.08% 96.39%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.51% 95.89%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.57% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.09% 97.09%
CHEMBL255 P29275 Adenosine A2b receptor 85.93% 98.59%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 84.31% 96.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.47% 86.33%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.10% 100.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 81.85% 100.00%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 81.02% 88.84%
CHEMBL3231 Q13464 Rho-associated protein kinase 1 80.22% 95.55%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 80.02% 89.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 3036626
LOTUS LTS0070989
wikiData Q83082637