7',3',4'-Trihydroxy-5-methoxy-4-phenylcoumarin

Details

Top
Internal ID 2c948f3d-f599-4e42-afbe-b9e43481be00
Taxonomy Phenylpropanoids and polyketides > Neoflavonoids > Neoflavones
IUPAC Name 4-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxychromen-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H12O6/c1-21-13-5-9(17)6-14-16(13)10(7-15(20)22-14)8-2-3-11(18)12(19)4-8/h2-7,17-19H,1H3
InChI Key XHSQEMRVWPSWDD-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C16H12O6
Molecular Weight 300.26 g/mol
Exact Mass 300.06338810 g/mol
Topological Polar Surface Area (TPSA) 96.20 Ų
XlogP 2.00

Synonyms

Top
4-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxychromen-2-one
CHEBI:183619
4-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-2H-chromen-2-one
LMPK12100057
2H-1-benzopyran-2-one, 4-(3,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-
InChI=1/C16H12O6/c1-21-13-5-9(17)6-14-16(13)10(7-15(20)22-14)8-2-3-11(18)12(19)4-8/h2-7,17-19H,1H

2D Structure

Top
2D Structure of 7',3',4'-Trihydroxy-5-methoxy-4-phenylcoumarin

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.16% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.25% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 94.76% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.54% 86.33%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 92.79% 80.78%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 92.33% 99.15%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.06% 95.56%
CHEMBL3194 P02766 Transthyretin 91.69% 90.71%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.53% 89.00%
CHEMBL1951 P21397 Monoamine oxidase A 90.35% 91.49%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.96% 99.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.26% 96.09%
CHEMBL4940 P07195 L-lactate dehydrogenase B chain 85.55% 95.53%
CHEMBL1163101 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 85.13% 98.11%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.94% 99.23%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 82.98% 95.78%
CHEMBL5903 Q04771 Activin receptor type-1 82.41% 89.93%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.60% 90.71%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.36% 95.50%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Coutarea hexandra

Cross-Links

Top
PubChem 5324351
LOTUS LTS0196620
wikiData Q105328275