(24E)-3,4-hydroxycucurbita-5,24-diene-26-oic acid

Details

Top
Internal ID a69c1b39-cf94-48f6-8831-ab0c04edd454
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Cucurbitacins
IUPAC Name (E,6R)-6-[(3S,8R,9R,10S,13R,14S,17R)-3-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid
SMILES (Canonical) CC(CCC=C(C)C(=O)O)C1CCC2(C1(CCC3(C2CC=C4C3CCC(C4(C)C)O)C)C)C
SMILES (Isomeric) C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC[C@@]2([C@@]1(CC[C@@]3([C@H]2CC=C4[C@H]3CC[C@@H](C4(C)C)O)C)C)C
InChI InChI=1S/C30H48O3/c1-19(9-8-10-20(2)26(32)33)21-15-16-30(7)24-13-11-22-23(12-14-25(31)27(22,3)4)28(24,5)17-18-29(21,30)6/h10-11,19,21,23-25,31H,8-9,12-18H2,1-7H3,(H,32,33)/b20-10+/t19-,21-,23-,24-,25+,28+,29-,30+/m1/s1
InChI Key JMOPTHLWCJXLBX-MTPQQZNSSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C30H48O3
Molecular Weight 456.70 g/mol
Exact Mass 456.36034539 g/mol
Topological Polar Surface Area (TPSA) 57.50 Ų
XlogP 7.90

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of (24E)-3,4-hydroxycucurbita-5,24-diene-26-oic acid

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.25% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.38% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.95% 98.95%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 94.11% 93.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.88% 94.45%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.69% 93.56%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.82% 95.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.30% 100.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.31% 97.25%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.87% 90.71%
CHEMBL221 P23219 Cyclooxygenase-1 84.24% 90.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.80% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.71% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 83.31% 91.19%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.26% 95.89%
CHEMBL2514 O95665 Neurotensin receptor 2 82.52% 100.00%
CHEMBL1914 P06276 Butyrylcholinesterase 81.10% 95.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.58% 86.33%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 80.02% 82.69%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 15479506
LOTUS LTS0098365
wikiData Q77422195