12-Hydroxydihydrochelirubine

Details

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Internal ID e6704810-f4d7-4cb0-bbf8-347ad13971b9
Taxonomy Alkaloids and derivatives > Benzophenanthridine alkaloids > Dihydrobenzophenanthridine alkaloids
IUPAC Name 15-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-11-ol
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H17NO6/c1-22-7-13-19(17(24-2)6-18-21(13)28-9-27-18)12-3-14(23)10-4-15-16(26-8-25-15)5-11(10)20(12)22/h3-6,23H,7-9H2,1-2H3
InChI Key LEHAJESKGINQOW-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H17NO6
Molecular Weight 379.40 g/mol
Exact Mass 379.10558726 g/mol
Topological Polar Surface Area (TPSA) 69.60 Ų
XlogP 3.70

Synonyms

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12-Hydroxychelirubine
131984-77-5
15-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-11-ol
5-methoxy-13-methyl-13,14-dihydro-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-7-ol
C05193
CHEBI:15716
DTXSID40331502

2D Structure

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2D Structure of 12-Hydroxydihydrochelirubine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 99.03% 96.77%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.98% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.71% 96.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.39% 93.40%
CHEMBL4208 P20618 Proteasome component C5 93.31% 90.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.78% 93.99%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 92.44% 91.79%
CHEMBL2581 P07339 Cathepsin D 92.28% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.74% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.01% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.75% 89.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.60% 92.62%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 88.96% 80.96%
CHEMBL2535 P11166 Glucose transporter 88.75% 98.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.23% 94.45%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 87.09% 82.67%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.70% 94.00%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 86.67% 89.62%
CHEMBL205 P00918 Carbonic anhydrase II 85.91% 98.44%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 85.03% 80.78%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.02% 95.89%
CHEMBL5747 Q92793 CREB-binding protein 82.43% 95.12%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 82.42% 82.38%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.99% 89.50%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.62% 90.24%
CHEMBL2047 Q96RI1 Bile acid receptor FXR 81.27% 96.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Eschscholzia californica

Cross-Links

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PubChem 440588
LOTUS LTS0063813
wikiData Q74416981