CDA2b

Details

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Internal ID c981bd82-5f20-4355-bddc-dd2206b00df9
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 3-[(3S,6S,9R,15S,18R,21S,24S,27R,30S,31R)-9-[(1S)-2-amino-2-oxo-1-phosphonooxyethyl]-15,21,24-tris(carboxymethyl)-18-(4-hydroxyphenyl)-30-[[(2S)-3-hydroxy-2-[(3-propyloxirane-2-carbonyl)amino]propanoyl]amino]-3,27-bis(1H-indol-3-ylmethyl)-31-methyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonazacyclohentriacont-6-yl]butanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C67H81N14O29P/c1-4-9-44-54(109-44)66(103)77-43(27-82)61(98)80-51-29(3)108-67(104)42(20-32-25-70-37-13-8-6-11-35(32)37)76-62(99)50(28(2)18-46(85)86)79-65(102)53(55(56(68)93)110-111(105,106)107)78-45(84)26-71-57(94)39(21-47(87)88)75-64(101)52(30-14-16-33(83)17-15-30)81-60(97)41(23-49(91)92)73-59(96)40(22-48(89)90)72-58(95)38(74-63(51)100)19-31-24-69-36-12-7-5-10-34(31)36/h5-8,10-17,24-25,28-29,38-44,50-55,69-70,82-83H,4,9,18-23,26-27H2,1-3H3,(H2,68,93)(H,71,94)(H,72,95)(H,73,96)(H,74,100)(H,75,101)(H,76,99)(H,77,103)(H,78,84)(H,79,102)(H,80,98)(H,81,97)(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H2,105,106,107)/t28?,29-,38-,39+,40+,41+,42+,43+,44?,50+,51+,52-,53-,54?,55+/m1/s1
InChI Key WTMASHWTLVHXAV-OQOVWUBXSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C67H81N14O29P
Molecular Weight 1577.40 g/mol
Exact Mass 1576.50314960 g/mol
Topological Polar Surface Area (TPSA) 690.00 Ų
XlogP -4.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of CDA2b

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.67% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.30% 96.09%
CHEMBL2581 P07339 Cathepsin D 99.01% 98.95%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 97.60% 91.71%
CHEMBL255 P29275 Adenosine A2b receptor 97.29% 98.59%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.04% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.92% 95.56%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 96.74% 93.10%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 96.59% 97.64%
CHEMBL3837 P07711 Cathepsin L 95.53% 96.61%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.59% 89.00%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 92.94% 83.10%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 92.27% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.16% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.86% 97.14%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 91.50% 97.43%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 91.42% 91.81%
CHEMBL3310 Q96DB2 Histone deacetylase 11 89.60% 88.56%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 89.29% 97.23%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.95% 90.08%
CHEMBL3401 O75469 Pregnane X receptor 87.85% 94.73%
CHEMBL226 P30542 Adenosine A1 receptor 86.29% 95.93%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 86.17% 96.11%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.65% 99.17%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 85.53% 95.83%
CHEMBL1949 P62937 Cyclophilin A 84.78% 98.57%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 84.68% 95.71%
CHEMBL4071 P08311 Cathepsin G 83.53% 94.64%
CHEMBL4588 P22894 Matrix metalloproteinase 8 82.74% 94.66%
CHEMBL340 P08684 Cytochrome P450 3A4 82.63% 91.19%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 81.73% 95.00%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 81.62% 94.23%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 81.52% 82.86%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 80.99% 90.93%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 80.67% 99.15%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139588772
LOTUS LTS0213771
wikiData Q105312643